Results 31 to 40 of about 403,985 (282)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Revealing the role of sealing treatment on the electrochemical corrosion properties of HVOF-sprayed WC–20Cr3C2–7Ni/MWCNTs coating

Journal of Materials Research and Technology, 2023
In this study, the WC–20Cr3C2–7Ni/MWCNTs coating was prepared by high-velocity oxy-fuel (HVOF) spraying. Coatings were sealed with two types of sealants (i.e., silicone resin and aluminum phosphate) using both conventional and vacuum impregnations ...
Jiyue Qin, Zheng Wei, Ziyu Wei, Kailin Wang, Sheng Hong   +4 more
doaj   +1 more source

Desidratação e caracterização físico-química de maçãs impregnadas com lactato de cálcio [PDF]

, 2013
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia de Alimentos, Florianópolis, 2013.A impregnação a vácuo (IV) de alimentos porosos consiste na troca do gás e/ou líquido ...
Assis, Fernanda Rosa
core  

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Optimization of Vacuum Impregnation with Aqueous Extract from Hibiscus sabdariffa Calyces in Apple Slices by Response Surface Methodology: Effect on Soluble Phenols, Flavonoids, Antioxidant Activity, and Physicochemical Parameters

Applied Sciences
Vacuum impregnation (VI) of natural extracts is often used as a pretreatment for fruit dehydration. Apple slices were subjected to VI [XVP: vacuum pressure (−0.4 to −0.2 mbar), XIT: impregnation time (2–10 min), and XRT: restoration time (1–3 min)] of ...
Luis Miguel Anaya-Esparza, Ernesto Rodríguez-Lafitte, Zuamí Villagrán, Edward F. Aurora-Vigo, José Martín Ruvalcaba-Gómez, Walter Bernardo Símpalo-López, Fernando Martínez-Esquivias, Cristhian Henry Sarango-Córdova   +7 more
doaj   +1 more source

Propriedades físico-químicas e de textura de abacaxi (var. Pérola) desidratado enriquecido com cálcio por impregnação a vácuo [PDF]

, 2014
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia de Alimentos, Florianópolis, 2014.O processo de impregnação a vácuo (IV) em alimentos porosos consiste na troca do gás e/ou ...
Lima, Marla Mateus de
core  

THE USE OF VACUUM IMPREGNATION TECHNOLOGY TO IMPROVE SMOKING PROCESS [PDF]

, 2015
One of the new technologies contributing to preserve of the original properties of food (as fruit or vegetables or fish) is vacuum impregnation. Vacuum impregnation is one method to preserve foods using vacuum and pressure to fill the porous with osmotic
null null, G Gunawan, Rodiah Nurbaya Sari, Sari, Rodiah Nurbaya, Diah L iah L. Ayudiarti, iah L. Ayudiarti, Diah L, Gunawan, G   +6 more
core   +2 more sources

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Mechanical Evaluation of Vegetal Fibers Impregnated in Vacuum in the Cultivation of Pea (Pisum sativum L.)

Journal of Natural Fibers, 2022
The kinetics of loss of mechanical properties in fique and cotton fibers impregnated in vacuum were evaluated as substitution alternative to the polypropylene fiber in the vertical support of the pea crop.
Leandro Geovanny Bravo Asmaza, Oswaldo Osorio Mora, David Fernando López Enríquez   +2 more
doaj   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source