Results 101 to 110 of about 345 (262)

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

Advanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li, Bin Zhang, Zhiqiu Zhang, Bing Zheng, Linhui Han, Chen Yan, Jialin Li, Kaiqiang Sun, Tianyi Zhao, Jiangang Shi   +9 more
wiley   +1 more source

Lysine 2-Hydroxyisobutyrylation- and Succinylation-Based Pathways Act Inside Chloroplasts to Modulate Plant Photosynthesis and Immunity. [PDF]

Adv Sci (Weinh), 2023
Chen B, Wang Z, Jiao M, Zhang J, Liu J, Zhang D, Li Y, Wang G, Ke H, Cui Q, Yang J, Sun Z, Gu Q, Wang X, Wu J, Wu L, Zhang G, Wang X, Ma Z, Zhang Y.   +19 more
europepmc   +1 more source

Electrocatalytic CO2 Reduction over Sn‐Cu Bimetallic Catalysts Synthesized via an Amalgamated Lithium Metal Method

Advanced Science, EarlyView.
An amalgamated lithium metal method enables systematic control of Sn–Cu active‐site dimensions from isolated atoms to nanocrystallites. Increasing the metal loading shifts CO2 electroreduction selectivity from acetaldehyde on highly dispersed Sn–Cu sites to formate on Sn‐rich crystallites, revealing how bimetallic dispersion and local coordination ...
Minghao Xie, Shichen Guo, Jianxin Wang, Haozhe Zhang, Xun Zhan, Lauren Valentino, Di‐Jia Liu   +6 more
wiley   +1 more source

Electronic Chip‐Mimetic Medical Implants for Controllable Sonothermal Treatments

Advanced Science, EarlyView.
Inspired by the thermal effect of working electronic chips, which consist of various heterostructures, an sonothermal‐responsive platform has been developed through constructing metal‐semiconductor interface on implants. Biofilm infection and deep vein thrombosis can be successfully treated by controllable ultrasound treatments.
Zhengdong Zhang, Pan Liu, Jie Lei, Shuchang Peng, Qiu Chen, Wei Guan, Yizhou Zhu, Gang Liu, Xiaobo Feng, Cao Yang, Lei Tan   +10 more
wiley   +1 more source

Effect of an Antioxidant Based on Red Beetroot Extract on the Abiotic Stability of Polylactide and Polycaprolactone. [PDF]

Molecules, 2021
Drohsler P, Cisar J, Sopik T, Sedlarik V, Pummerova M.   +4 more
europepmc   +1 more source

Single‐Dose TACE‐Like Injection of Sustained‐Release Panobinostat/IL‐12 Polymeric Microparticles is Effective in Preclinical Liver Cancer Models

Advanced Science, EarlyView.
A novel PLGA/PBAE polymer microparticle platform revolutionizes intermediate‐stage liver cancer treatment by co‐delivering panobinostat and IL‐12 via a single TACE‐like injection. This sustained‐release system overcomes tumor immunosuppression, triggers robust innate and adaptive immune responses, and establishes tertiary lymphoid structures ...
Hongzhe Yu, Ling Li, Sachin S. Surwase, Xin Ming M. Zhou, Hongtao Qian, Joel C. Sunshine, Florin M. Selaru, Jordan J. Green   +7 more
wiley   +1 more source

Reconstruction of motor control circuits in adult Drosophila using automated transmission electron microscopy. [PDF]

Cell, 2021
Phelps JS, Hildebrand DGC, Graham BJ, Kuan AT, Thomas LA, Nguyen TM, Buhmann J, Azevedo AW, Sustar A, Agrawal S, Liu M, Shanny BL, Funke J, Tuthill JC, Lee WA.   +14 more
europepmc   +1 more source

Thermal‐Ionic Coupling in Transpiration‐Inspired Janus Nanofiber Membranes: Synergistic Dry‐Wet Interface Engineering for Solar‐Driven Electricity Generation

Advanced Science, EarlyView.
A transpiration‐inspired Janus nanofiber membrane creates a persistent dry‐wet interface that couples localized solar heating with hydration‐induced ion regulation. The asymmetric architecture sustains directional water and ion transport, suppresses salt accumulation, and enables simultaneous seawater evaporation and stable electricity generation ...
Qin Su, Haidi Wu, Tingting Zheng, Di He, Huaiguo Xue, Longcheng Tang, Yongqian Shi, Xuejun Lai, Jiefeng Gao, Wancheng Gu, Jun Yan   +10 more
wiley   +1 more source

A Modular Variable Stiffness Co‐Bot System Achieving Tasks Flexibility and Contact Compliance

Advanced Science, EarlyView.
Bio‐inspired antagonistic compliance enables a modular rigid‐soft co‐bot platform with variable stiffness for safe human‐robot interaction (HRI): Standardized interfaces support application‐driven configurations with tailored DoFs, workspace, and stiffness range, making the system suited to HRI and low‐volume automation.
Wenlong Gaozhang, Yue Li, Jialei Shi, Yaxi Wang, Kaspar Althoefer, Agostino Stilli, Helge A. Wurdemann   +6 more
wiley   +1 more source

A Photothermally Amplified Enzyme–Nitric Oxide Co‐Regulatory System Reprograms Pathological ECM–Fibroblast Crosstalk to Alleviate Hypertrophic Scarring

Advanced Science, EarlyView.
An enzyme–nitric oxide (NO) co‐regulatory strategy reprograms pathological extracellular matrix (ECM)–fibroblast crosstalk in hypertrophic scars. Enzymatic degradation of pre‐existing ECM relieves aberrant mechanical cues, while NO‐mediated fibroblast phenotypic modulation restrains excessive collagen synthesis.
Junzhe Fu, Fan Jia, Yixian Mu, Wanzhe Liu, Dingqi Tang, Qiao Jin, Jian Ji, Youxiang Wang   +7 more
wiley   +1 more source