Results 131 to 140 of about 363,802 (281)
Advanced Science, Volume 13, Issue 25, 4 May 2026.TRIM25 acts as a multifunctional hub driving intervertebral disc degeneration under mechanical stress. Mechanical compression significantly upregulates TRIM25 expression, establishing it as a key E3 ubiquitin ligase platform. TRIM25 targets PARG and Ku80 via distinct molecular interfaces, triggering their ubiquitination and degradation.
Zhangrong Cheng +9 more
wiley +1 more source
AntioxidantsThis study explores whether molecular hydrogen (H2) administration can alleviate cognitive and immunological disturbances in a mouse model of vascular dementia (VaD).
Dain Lee, Hyunjun Jo, Jong-Il Choi
doaj +1 more source
Drug Development Research, Volume 87, Issue 3, May 2026.ABSTRACT Omics’ technologies have enabled clinicians to gain previously unprecedented insights into the molecular complexity and clinical heterogeneity of triple‐negative breast cancer (TNBC). Increasingly it is being realized that TNBC does not respond well to current targeted therapies.
Ya‐Ting Chuang +6 more
wiley +1 more source
Stroke and Vascular NeurologyVascular dementia (VaD) is the second leading cause of dementia after Alzheimer’s disease (AD). In comparison to AD, there is a decline in the incidence of VaD due to recent improvements in cardiovascular risk factors. Brain hypoperfusion and hypoxia due
Jeffrey Chen +6 more
doaj +1 more source
The impact of metal cup size on neonatal and maternal morbidity in vacuum‐assisted deliveries
International Journal of Gynecology &Obstetrics, Volume 173, Issue 2, Page 757-762, May 2026.Abstract Objective To evaluate whether metal cup size influences maternal and neonatal morbidity in vacuum‐assisted deliveries (VAD). Materials and Methods Retrospective cohort at a single tertiary center (2011–2022) comparing 60‐mm versus 50‐mm Malmström cups. A 1:1 matched cohort analysis balanced maternal and obstetric variables.
Matan Anteby +6 more
wiley +1 more source
Vad hjälper och vad stjälper antimobbningsarbete?
, 2013 Såväl internationell som nationell forskning påvisar att flertalet antimobbningsprogram samt antimobbningskomponenter, som av forskare och experter förordats, i många fall kan vara ineffektiva tillika kontraeffektiva. Då varje fall av mobbning är unikt blir således metoden att bekämpa det också sådant.
openaire +1 more source
Development of CAR Exosomes Targeting FAP for the Treatment of Intrauterine Adhesion
Journal of Extracellular Vesicles, Volume 15, Issue 5, May 2026.ABSTRACT Engineered extracellular vesicles (EVs) have emerged as promising cell‐free platforms for immunomodulation and tissue repair. In this study, we generated EVs derived from chimeric antigen receptor (CAR) T cells targeting fibroblast activation protein (FAP) and investigated their biological and therapeutic functions.
Wenyan Fu +8 more
wiley +1 more source
Changes in adiponectin system after ventricular assist device in pediatric heart failure
JHLT OpenBackground: Ventricular assist device (VAD) implant represents a therapeutic option for pediatric patients with end-stage heart failure (HF). Heart unloading by VAD can modify several molecular pathways underlying cardiac function in HF.
Rosetta Ragusa +7 more
doaj +1 more source
Articulating Sovereignties: Struggles for Subaltern Hegemony in Ecuador and Bolivia
Antipode, Volume 58, Issue 3, May 2026.ABSTRACT This article examines the cycles of articulation and disarticulation between working‐class and indigenous‐campesino movements in Ecuador and Bolivia. While the former advances national‐popular sovereignty, aiming to strengthen the state against imperialism, the latter defends community‐territorial sovereignty against internal colonialism ...
Diego Andreucci +3 more
wiley +1 more source