Results 161 to 170 of about 189,091 (334)

Artificial intelligence in preclinical epilepsy research: Current state, potential, and challenges

open access: yesEpilepsia Open, EarlyView.
Abstract Preclinical translational epilepsy research uses animal models to better understand the mechanisms underlying epilepsy and its comorbidities, as well as to analyze and develop potential treatments that may mitigate this neurological disorder and its associated conditions. Artificial intelligence (AI) has emerged as a transformative tool across
Jesús Servando Medel‐Matus   +7 more
wiley   +1 more source

Heart Rate Variability Features as Predictors of Intermittent Theta‐Burst Stimulation Response in Posttraumatic Stress Disorder

open access: yesNeuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Background Posttraumatic stress disorder (PTSD) is associated with autonomic dysfunction as indicated by deficits in the sympathetic and parasympathetic nervous systems. These abnormalities are expressed as elevated heart rate and reduced heart rate variability (HRV), respectively.
Camila Cosmo   +4 more
wiley   +1 more source

Real‐world effectiveness of highly purified cannabidiol in epilepsy associated with 15q11.2‐q13.1 duplication and deletion syndromes: A multicenter study

open access: yesEpilepsia Open, EarlyView.
Abstract This multicenter retrospective study evaluated the effectiveness and safety of highly purified cannabidiol (CBD) in 22 patients with 15q11.2‐q13.1 duplication or deletion syndromes (15q‐DDS), including 12 with 15q duplication syndrome (dup15q) and 10 with Angelman syndrome (AS). Median (interquartile range [IQR]) age at CBD initiation was 14.5
Emanuele Cerulli Irelli   +14 more
wiley   +1 more source

Effectiveness of adjunctive low‐dose clobazam in adults with focal drug‐resistant epilepsy and incomplete response to cenobamate: A real‐world study

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Cenobamate (CNB) is a highly effective antiseizure medication (ASM) for focal drug‐resistant epilepsy (DRE); nevertheless, even with CNB treatment and optimized therapy, a substantial proportion of patients continued to experience seizures.
Ilaria Ciullo   +8 more
wiley   +1 more source

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

open access: yesIbrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source

The Laryngeal Auditory Startle Reflex (LASR): A New Component of the Auditory Startle Response

open access: yesThe Laryngoscope, EarlyView.
The auditory startle reflex contains a distinct laryngeal component, termed the laryngeal auditory startle reflex (LASR). In healthy adults, the LASR is modulated by supratentorial influences and habituates to repetitive stimuli. Physiologic and pathologic implications for the LASR as a component of the overall human SR remain to be determined but may ...
Catherine F. Sinclair   +4 more
wiley   +1 more source

Vagal contributions to fetal heart rate variability: an omics approach

open access: yes, 2019
Fetal heart rate variability (fHRV) is an important indicator of health and disease, yet its physiological origins, neural contributions in particular, are not well understood.
Burns, Patrick   +7 more
core   +1 more source

Value‐Based Neuromonitoring in Thyroidectomy: A Comprehensive Cost–Utility Analysis

open access: yesThe Laryngoscope, EarlyView.
ABSTRACT Objective To compare the cost–utility of major intraoperative neuromonitoring (IONM) strategies in thyroidectomy across commercial platforms, and to quantify the impact of continuous IONM (CIONM), automated nerve trend monitoring, postoperative laryngoscopy policy, and technical failure on total episode costs and medicolegal burden.
Daqi Zhang   +4 more
wiley   +1 more source

Validation of the TruBlue Light Laser for Laryngeal Somatosensory and Perturbation Testing

open access: yesThe Laryngoscope, EarlyView.
This study validates a blue light laser method for assessing laryngeal somatosensory function by measuring perceptual thresholds, reflexive responses, discrimination acuity, and vocal perturbations in healthy adults. Results demonstrate that the method provides precise, reliable stimulation and yields quantifiable sensory and acoustic responses ...
Adrianna C. Shembel   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy