Results 51 to 60 of about 629,525 (256)

Rapid Fabrication of Self‐Propelled and Steerable Magnetic Microcatheters for Precision Medicine

Advanced Materials, EarlyView.
A rapid Joule heating fabrication method for the production of self‐propelling, adaptive microcatheters, with tunable stiffness and integrated microfluidic channels is presented. Demonstrated through three microrobotic designs, including a steerable guiding catheter, an untethered wave‐crawling TubeBot, and a distal‐end propelled microcatheter, it was ...
Zhi Chen, Boris Rivkin, David Castellanos‐Robles, Ivan Soldatov, Lukas Beyer, Mariana Medina‐Sánchez   +5 more
wiley   +1 more source

Laparoscopic uterosacral ligament suspension: a systematic review and meta-analysis of safety and durability

Frontiers in Surgery, 2023
IntroductionPelvic organ prolapse (POP) is a widespread condition affecting from 40% to 60% of women. Reconstructive vaginal surgeries are the most commonly performed procedures to treat POP.
Carlo Ronsini, Carlo Ronsini, Francesca Pasanisi, Francesca Pasanisi, Stefano Cianci, Maria Giovanna Vastarella, Marika Pennacchio, Marika Pennacchio, Marco Torella, Marco Torella, Alfredo Ercoli, Nicola Colacurci, Nicola Colacurci   +12 more
doaj   +1 more source

Ovarian Matrisome Dynamics and αvβ3‐Mediated Regulation in Early Follicular Development

Advanced Science, EarlyView.
The matrisome undergoes dynamic remodeling during early follicular development. Integrin αvβ3 mediates matrisome signals, regulating primordial follicle activation/atresia and secondary follicle growth via Hippo/mTOR pathways, with conserved roles in human ovaries, offering therapeutic targets for ovarian disorders.
Tong Wu, Yanzhi Feng, Qingqing Zhu, Ting Jiang, Yueyue Gao, Kebing Nie, Xianan Tang, Ying Chen, Dianxing Hu, Xudan Yang, Shixuan Wang, Meng Wu, Jinjin Zhang   +12 more
wiley   +1 more source

A Comparison of the Ovulation Method With the CUE Ovulation Predictor in Determining the Fertile Period [PDF]

, 1996
The purpose of this study was to compare the CUE Ovulation Predictor with the ovulation method in determining the fertile period. Eleven regularly ovulating women measured their salivary and vaginal electrical resistance (ER) with the CUE, observed their
Albrecht B., Corson G., Corson S. L., Doud J., Fehring R., Fernando R., Fernando R. S., Fernando R. S., Hilgers T. W., Hilgers T. W., Hilgers T. W., Hilgers T. W., Jacobs M. H., Moreno J. E., Roumen F., Royston P., Seibel M.   +16 more
core   +2 more sources

Remimazolam Ameliorates Autistic‐Like Behaviors via Suppression of Ferroptosis in VTA Dopaminergic Neurons in a Mouse Model of ASD

Advanced Science, EarlyView.
The ultra‐short‐acting sedative remimazolam has a sustained therapeutic effect on the core symptoms of VPA‐exposed mice. Remimazolam, a GABA agonist, exerts its therapeutic effects by protecting dopamine neurons in the VTA of VPA‐exposed mice. Meanwhile, ferroptosis is the critical mechanism by which remimazolam protects VTA dopaminergic neurons and ...
Yuxin Zhang, Jianwei Lin, Chaoyang Tong, Xin Fu, Mengqin Shan, Yue Huang, Kan Zhang, Jijian Zheng   +7 more
wiley   +1 more source

Case report: a robotic-vaginal approach for total vaginectomy and hysterectomy with pelvic sentinel lymph node dissection in primary vaginal melanoma: a 10-step technique and literature review

Frontiers in Surgery, 2023
IntroductionPrimary vaginal melanoma is extremely rare, has a poor prognosis, and occurs mostly in elderly women. The diagnosis is based on histology and immunohistochemistry of a biopsy.
Philippe Van Trappen, Ines Lebbe, Eveline De Cuypere, Nele Claes   +3 more
doaj   +1 more source

Role of lactobacilli and lactoferrin in the mucosal cervicovaginal defense [PDF]

, 2018
Human lactoferrin is an iron-binding glycoprotein present at high concentrations in breast milk and colostrum. It is produced by many exocrine glands and widely distributed in a variety of body fluids.
Aagaard, Abramov, Agerberth, Aldunate, Alexander, Allsworth, Anahtar, Ando, Appelmelk, Aroutcheva, Ashida, Baker, Baranger, Beigi, Berlutti, Berlutti, Berlutti, Bradshaw, Bradshaw, Britigan, Brooks, Brotman, Bullen, Byrne, Caccavo, Cauci, Cherpes, Cole, Cole, Conti, Corbin, Corbishley, Cutone, Cutone, De Gregorio, Deese, Delgado-Rizo, Drannik, Elass, Ericksen, Eschenbach, Eslami, Frioni, Fritsch, Gajer, He, He, Hearps, Hedges, Hein, Hemalatha, Hickey, Hiemstra, Hill, Hill, Hudić, Hummelen, Jakobsson, Judd, Kaushic, Kelver, Klebanoff, Kohlhoff, Kościuczuk, Lamont, Larsen, Legrand, Legrand, Leitch, Maggi, Marrazzo, Martin, Martin, Mastromarino, Mastromarino, Mastromarino, Meijerink, Michieli, Moberg, Morrison, Morrison, Nardis, Ness, Niyonsaba, Olmsted, Olmsted, Omata, Ong, O’Hanlon, Paesano, Paesano, Paesano, Paesano, Paesano, Pazgier, Peipert, Peipert, Petrova, Pino, Puddu, Quayle, Rampersauda, Raulston, Ravel, Ravel, Redondo-Lopez, Reghunathan, Rizzo, Rizzo, Roberton, Rosa, Rönnqvist, Santiago, Santiago, Sarkar, Sessa, Shakibaei, Shust, Singh, Singh, Spadaro, Spear, Spurbeck, Srinivasan, Srinivasan, Stallmann, Straub, Stríz, Suzuki, Tachedjian, Teng, Teng, Teng, Tuyama, Valenti, Valenti, Valenti, Valore, Van de Wijgert, Vargas-Villavicencio, Vielfort, Vitali, Walther-António, Ward, Weinberg, Wiesenfeld, Wiesner, Wilson, Wilson, Wilson, Wira, Wira, Wira, Wira, Wu, Yamamoto, Zhou   +156 more
core   +2 more sources

Tim1 Deficiency Mediates Gestational Hyperglycemia‐Related Syncytiotrophoblast Dysfunction and Fetal Growth Restriction

Advanced Science, EarlyView.
Hyperglycemia during pregnancy impairs the fusion of trophoblast cells into syncytiotrophoblasts, leading to fetal growth restriction. This impaired fusion is mediated by Tim1 downregulation via hyperglycemia‐induced ROS. Antioxidant therapy during pregnancy promotes syncytiotrophoblast formation by upregulating Tim1 expression, thus alleviating fetal ...
Junsen She, Rui Liu, Chen Fang, Shuyu Zhang, Yizhi Hu, Fei Guo, Yuhang Long, Mengzhen Ding, Haiyan Wu, Bokang Zhou, Zexin Yang, Ying Jiang, Jianzhong Sheng, Ling Gao, Hefeng Huang   +14 more
wiley   +1 more source

Development of Mucoadhesive Gel Microbicide to Target Mucosal HIV Reservoirs [PDF]

, 2014
The wide use of microbicide is mainly depends on its effectiveness, less frequent application, ready availability and most importantly cost. The aim of this work was to develop affordable microbicide mucoadhesive gel formulation of synthetic anti HIV ...
Shegokar, Ranjita, Singh, Kamalinder K
core   +1 more source

Testicular mRNA‐LNP Delivery: A Novel Therapy for Genetic Spermatogenic Disorders

Advanced Science, EarlyView.
In the current study, we developed a novel therapy for genetic spermatogenic disorders. It was revealed that in vivo delivery of mRNA LNP3 could restore spermatogenesis in Msh5D486Y/D486Y and Maps KO mouse models with meiotic arrest. Notably, the offspring without genomic integration was born using ICSI derived from the rescue of Msh5D486Y/D486Y mouse ...
Chenwang Zhang, Nan Liang, Wenbo Li, Shuai Xu, Peng Li, Wanze Ni, Na Li, Sha Han, Ningjing Ou, Haowei Bai, Yuxiang Zhang, Furong Bai, Yifan Sun, Dewei Qian, Xinjie Bu, Erlei Zhi, Ruhui Tian, Yuhua Huang, Jingpeng Zhao, Fujun Zhao, Hao Chen, Zheng Li, Chencheng Yao   +22 more
wiley   +1 more source