Results 71 to 80 of about 629,525 (256)

Role of Lactobacillus crispatus in vaginal infections: insights from metagenomics and metabolomics studies [PDF]

open access: yes, 2019
Objective: Lactobacillus spp. constitute the most prevalent bacterial microorganism in the vaginal milleu. Several probiotic mechanisms have been associated with Lactobacillus, but the most relevant one is lactate production – resulting in a low pH value,
Donder, G.   +5 more
core  

Sphingomonas paucimobilis‐Driven Epithelial–Endothelial Transition in Adenomyosis Pathogenesis

open access: yesAdvanced Science, EarlyView.
This study identifies epithelial–endothelial transition (EET) as a novel adenomyosis pathogenic mechanism driven by Sphingomonas paucimobilis colonization. Systematic inhibitor experiments validate a TNFα→NF‐κB→MMP signaling cascade essential for EET. Critically, bacterial culture supernatant fails to induce pathological changes, demonstrating viable ...
Peigen Chen   +7 more
wiley   +1 more source

Maternal Preconception Antibiotic Exposure Disrupts Microbial Succession: A Transgenerational Risk for Offspring Gut Mucosal Immaturity and Colitis Susceptibility

open access: yesAdvanced Science, EarlyView.
This study reveals that maternal antibiotic exposure prior to conception disrupts intergenerational gut microbial succession. By enhancing maternal‐offspring microbial transmission, altering microbial developmental trajectories and increasing selective pressures during community assembly, these disturbances lead to persistent gut mucosal immaturity and
Yuzhu Chen   +8 more
wiley   +1 more source

Surfactant Protein D Reverses the Gene Signature of Transepithelial HIV-1 Passage and Restricts the Viral Transfer Across the Vaginal Barrier

open access: yesFrontiers in Immunology, 2019
Effective prophylactic strategy against the current epidemic of sexually transmitted HIV-1 infection requires understanding of the innate gatekeeping mechanisms at the genital mucosa.
Hrishikesh Pandit   +10 more
doaj   +1 more source

Lactobacillus crispatus as the etiological agent in cytolytic vaginosis [PDF]

open access: yes, 2019
Introduction: Lactobacillus spp. dominate the vaginal niche but can also be involved in other vaginal dysbiosis, such as cytolytic vaginosis (CV), which remains poorly studied.
Donders, G   +6 more
core  

Diversity Patterns of Domestic Herbivore Viruses in China Reveal Transmission Dynamics with Disease Management Implications

open access: yesAdvanced Science, EarlyView.
This study performs pan‐viromic profiling of 14,529 samples from 5,710 domestic herbivores across five Chinese provinces, establishing the DhCN‐Virome (1,085,360 viral metagenomes). It reveals species/sample‐specific viromic signatures and cross‐species transmission dynamics, aiding unified disease control.
Yue Sun   +19 more
wiley   +1 more source

Non-Descent Vaginal Hysterectomy - Analysis of 100 Cases

open access: yesAsian Journal of Medical Sciences, 2013
OBJECTIVE: To evaluate the feasibility of performing vaginal hysterectomy for non-prolapsed uteri as primary route METHODS: 100 patients planned for hysterectomy for a wide range of indications like large uterus, cervix flushed with vagina, previous ...
Soma Bandyopadhyay, Manidip Pal
doaj   +1 more source

Enhancement of Opioid-Mediated Analgesia\ud by Ingestion of Amniotic Fluid:\ud Onset Latency and Duration [PDF]

open access: yes, 1989
Ingestion of placenta and amniotic fluid has been shown to enhance opioid-mediated analgesia produced by morphine injection, footshock, vaginal/cervical stimulation, and during late pregnancy in rats.
Doerr, Jean C., Kristal, Dr. Mark B.
core  

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