Results 101 to 110 of about 2,362,904 (300)

Human evolution and the obstetrical dilemma: The pelvic floor hypothesis

open access: yesThe Anatomical Record, EarlyView.
Abstract Human childbirth is mechanically difficult because a large‐headed, broad‐shouldered fetus must pass through a comparatively narrow, twisted bony birth canal. Traditional explanations of this “obstetrical dilemma” emphasize the role of bipedal locomotion in inhibiting the evolution of a wider, more spacious pelvis.
Barbara Fischer, Ekaterina Stansfield
wiley   +1 more source

Research progress on the correlation between gestational vaginal microecology and vaginal infectious diseases

open access: yes, 2018
The health status of the vaginal microenvironment, a complicated system, is an important indicator of female reproductive health. The vaginal flora is in a state of balance, and the microorganisms coexist and are interdependent to maintain the vaginal ...
Haiwei Dong, Xiaohui Yang
core   +1 more source

Monitoring pharmacodynamic and molecular drug targets in liquid biopsy: Exploratory study in liver cancer with modelling of EGFR Receptor engagement

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Liquid biopsy is minimally invasive (compared with tissue biopsy) and has previously been used to generate systems data regarding drug elimination via hepatic enzymes and transporters. This study extends quantitative assessment of systems parameters in liquid biopsy to pharmacodynamic (PD) and disease markers relevant to cancer development
Zubida M. Al‐Majdoub   +3 more
wiley   +1 more source

Understanding and Preventing Recurring Bacterial Vaginosis: Important Considerations for Clinicians

open access: yesInternational Journal of Women's Health, 2023
Christina A Muzny,1 Jack D Sobel2 1Division of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA; 2Division of Infectious Diseases, Department of Medicine, Wayne State University, Detroit, MI ...
Muzny CA, Sobel JD
doaj  

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

open access: yesBMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim   +9 more
wiley   +1 more source

High prevalence and incidence of human papillomavirus in a cohort of healthy young African female subjects. [PDF]

open access: yes, 2013
OBJECTIVES: We measured the prevalence and incidence of human papillomavirus (HPV) infection in young female subjects recruited for a safety and immunogenicity trial of the bivalent HPV-16/18 vaccine in Tanzania.
Mayaud, Philippe   +10 more
core   +1 more source

Circular Economy in the Healthcare Industry: Developing a Circularity Assessment Tool for Complex Medical Devices

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT As the circular economy transition gains traction in the healthcare sector, extending the lifespan of complex medical devices has become a key priority, given their high cost and the challenges associated with their technological sophistication.
Tetiana Shevchenko   +7 more
wiley   +1 more source

Bacterial Vaginosis and Trichomononiasis. Fundamental World Guidelines on Management and Therapy of the Patients

open access: yesАнтибиотики и Химиотерапия, 2020
The vaginal discharge is one of the most frequent symptoms requiring medical advise. Vaginal discharges are mainly associated with three diseases: bacterial vaginosis, trichomononiasis and candidiasis.
M. A. Gomberg
doaj  

HPV and HPV-associated cervical diseases in women, who use hormonal methods of contraception: diagnostic and treatment management of abnormal cytology test result

open access: yesМедицинский совет, 2019
If abnormal cytology test results are identified in the users of hormonal methods of contraception, including a vaginal ring, they should adhere to diagnostic algorithms aimed at identifying and treating HPV-associated cervical diseases. NovaRing vaginal
N. M. Nazarova   +2 more
doaj   +1 more source

VAGINAL HYSTERECTOMY FOR SUPPURATIVE DISEASE AND ITS RESULTS. [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1895
Since we have found that the uterus may be removed by the vagina with less shock to the patient than by the abdominal method, we may consider the operation of abdominal hysterectomy as well applied to other diseased conditions than cancer, for which the operation was first designed. Dr.
openaire   +1 more source

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