Results 81 to 90 of about 2,362,904 (300)

WFS1 Deficiency Impairs PIAS4‐Associated SUMOylation and Increases Ubiquitin‐Mediated Spermatogenesis‐Related Protein Degradation Leading to Testicular Male Infertility

open access: yesAdvanced Science, EarlyView.
The findings establish a critical role for WFS1 in human male fertility. Mechanistically, WFS1 interacts with PIAS4 to promote the SUMOylation of key spermatogenesis‐associated proteins, which in turn competitively inhibits their K48‐linked ubiquitin‐mediated degradation during spermatogenesis.
Yunchuan Tian   +14 more
wiley   +1 more source

Diagnosis of biocenosis of the vagina of women with recurrent miscarriages

open access: yesRUDN Journal of Medicine, 2016
We investigated the vaginal microbiome of 67 patients with threatened pregnancy using bacterioscopic method and qPCR of vaginal swabs, vaginal pH measurement, and FISH to evaluate desquamated epithelial cells of vagina in urine sediments.
G Ph Totchiyev   +4 more
doaj  

Functional testing is a complementary tool for the diagnosis of vaginitis

open access: yesBMC Women's Health
Objective Vaginal microbiota evaluation is a methodology widely used in China to diagnose various vaginal inflammatory diseases. Although vaginal microbiota evaluation has many advantages, it is time-consuming and requires highly skilled and experienced ...
Danqin Feng   +7 more
doaj   +1 more source

Laparoscopic Versus Open Surgery for Diverticular Disease: A Structured Review Across Clinical Settings and Operative Strategies

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Laparoscopic surgery is increasingly used to treat colonic diverticulitis; however, its role in emergency, perforated, high‐risk, and procedure‐specific settings remains uncertain. This structured narrative review evaluated and synthesized comparative evidence by clinical setting, operative strategy, and patient risk profile to provide a ...
Marie Hanaoka   +4 more
wiley   +1 more source

Comparison between Effectiveness of Lactobacillus Acidophilus Suppository and Metronidazole Vaginal Tablet with Aim of Regulation of Vaginal PH in Patients with Bacterial Vaginosis [PDF]

open access: yes
Background & Objectives: Increase in vaginal pH is an indicator of bacterial vaginosis , changing a healthy acidic environment to a more acidic than 4.5.
محمدپوراصل, اصغر   +5 more
core  

Validity of coital diaries in a feasibility study for the Microbicides Development Programme trial among women at high risk of HIV/AIDS in Mwanza, Tanzania.

open access: yes, 2007
OBJECTIVES: To compare coital diaries and face-to-face interviews (FFIs) in measuring sexual behaviour among women at high risk of HIV. To assess the effect of differing levels of support from researchers on reporting in coital diaries and FFIs. METHODS:
Desmond, Nicola A   +25 more
core   +1 more source

B/ordering and healthcare access for migrants with precarious status: The role of healthcare workers in counteracting restrictive policies

open access: yesAmerican Journal of Community Psychology, EarlyView.
Abstract In Canada, precarious migration is largely invisibilized. Nonetheless, b/ordering greatly affects people's realities by limiting access to social rights. In Quebec, migrants with precarious status (MPS) do not have access to healthcare, although Quebec has a “universal” healthcare coverage.
Émilie Pigeon‐Gagné   +3 more
wiley   +1 more source

Pediatric Vaginal Discharge

open access: yesInternational Journal of Tropical Veterinary and Biomedical Research, 2018
Vaginal discharges are commonly seen in the pediatric population, approximately more than 50% of all pediatric genital complaints. Normal vaginal secretion is usually thin, and clear to white with a variable amount, while malodorous, abnormal consistency
Fitria Salim, Sitti Hajar
doaj   +1 more source

Bacterial vaginosis in female facility workers in north-western Tanzania: prevalence and risk factors. [PDF]

open access: yes, 2009
OBJECTIVES: To determine prevalence of, and risk factors for, bacterial vaginosis (BV) among herpes simplex virus (HSV) 2 seropositive Tanzanian women at enrollment into a randomised, placebo-controlled trial of HSV suppressive treatment.
Ross, D   +35 more
core   +1 more source

Expanded Phenotype Associated With an Intronic PPP1R12A Variant: A Case Report and Literature Review

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Autosomal dominant PPP1R12A‐related genitourinary and/or brain malformation syndrome is a recently described multisystem disorder caused by loss‐of‐function variants in the protein phosphatase 1 regulatory subunit 12a (PPP1R12A) gene. To date, 22 affected individuals have been reported with variable brain malformations and genitourinary ...
Emily M. Bland   +4 more
wiley   +1 more source

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