Results 201 to 210 of about 2,362,904 (300)

Conserved SERPINE2 function maintains ovarian estrogen production to support fertility in goats and mice

open access: yesiMetaOmics, EarlyView.
Single‐nucleus RNA sequencing and functional profiling of goat ovaries with divergent litter sizes revealed prolificacy‐associated granulosa cell (GC) states characterized by enhanced proliferation‐ and steroidogenesis‐related features, together with altered predicted cell–cell communication.
Sanbao Zhang   +6 more
wiley   +1 more source

The Vaginal Microbiome in Health and Disease

open access: yes
There are different compositions characterizing a healthy vaginal microbiota, typically characterized by a dominance of Lactobacilli and an acidic pH milieu, constituting the primary barrier against pathogenic intrusion. Even subtle perturbations can precipitate various clinical presentations or adverse obstetric outcomes. The vaginal microbial balance
openaire   +1 more source

Evaluation of Ceftriaxone as a Monotherapy and Amoxicillin With Clavulanic Acid as Combination Therapy in Surgical Prophylaxis

open access: yesiNew Medicine, EarlyView.
ABSTRACT Surgical antibiotic prophylaxis (SAP) is crucial in preventing postoperative surgical site infections (SSIs), especially in clean and clean‐contaminated surgeries. It was a prospective comparative observational study that compared the effectiveness and safety of single‐dose ceftriaxone monotherapy with amoxicillin–clavulanic acid as a ...
Anayat Ullah   +5 more
wiley   +1 more source

Paraneoplastic Fever in a Patient With Cervical Carcinoma: A Diagnostic Challenge and Management Approach. [PDF]

open access: yesCase Rep Oncol Med
Masilenge I   +6 more
europepmc   +1 more source

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

open access: yesiNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid   +4 more
wiley   +1 more source

Exploring vaginal microbiota–tissue resident stem cell crosstalk: VCAM1/Akt signaling ‐mediated enhancement of regenerative capacity

open access: yesInterdisciplinary Medicine, EarlyView.
Vaginal microbiota‐derived secretory factors enhance the regenerative capacity of human endometrial stem cells by upregulating VCAM1 and activating PI3K/Akt signaling. This microbiota–stem cell crosstalk promotes self‐renewal, migration, multilineage differentiation, and metabolic reprogramming in vitro and in vivo, establishing a novel microbiota ...
Soo‐Rim Kim   +6 more
wiley   +1 more source

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