Results 111 to 120 of about 226,558 (238)

A guide to host genetic determinants of female microbiome composition across distinct anatomical niches

The FEBS Journal, EarlyView.
Host genetic variation in immune regulation and cell signalling genes was associated with microbiome composition across vaginal, gut, oral and skin sites, while associations involving metabolic function, epithelial barrier integrity and hormonal processes were more site‐specific. Overall, our findings indicate that host genetic variation contributes to
Isabella Margaret Davidson, Elham Nikbakht, Hayley O'Neill, Larisa Margaret Haupt, Paul Joseph Dunn   +4 more
wiley   +1 more source

Pregnancy outcomes following exposure to galcanezumab: Analysis of cases from the galcanezumab clinical trials and postmarketing database

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective This study was conducted to describe pregnancy outcomes reported following maternal or paternal exposure to galcanezumab in clinical trials and postmarketing surveillance. Background Galcanezumab is a calcitonin gene‐related peptide‐inhibiting monoclonal antibody indicated for the preventive treatment of migraine.
Irene Boz, Jan Lewis Brandes, Christopher Robinson, Maria Fernanda Scantamburlo Fernandes, Sarah Lipsius, LaRonda Morford, Enemona Emmanuel Adaji, Anaclara Prada Jardim, Holland C. Detke   +8 more
wiley   +1 more source

The Impact of Hidradenitis Suppurativa on Sexual Function: A Multicentered Cross‐Sectional Study

International Journal of Dermatology, EarlyView.
Summary of a multicenter study of 522 patients with hidradenitis suppurativa (HS) evaluating quality of life, disease severity, and sexual function. HS was associated with impaired sexual function in both women and men, with pain identified as a central driver.
Defne Özkoca, Hediye Eker, Dilay Yerlioğlu Ak, Beril Kara Esen, Ali Emre Buğday, Tuğba Tehçi, Neslihan Demirel Öğüt, Ayris Öztürk, Algün Polat Ekinci, Özlem Su Küçük, Erkan Alpsoy, Aslı Tatlıparmak, Esra Adışen, Ecem Etli, Fatma Etgü, Gülhan Aksoy Saraç, Ersoy Acer, Esra Ağaoğlu, Münevver Güven, Zeynep Karaca Ural, Rabia Öztaş Kara, Ahmet Uğur Atılan, Gözde Ulutaş Demirbaş, Gülhan Gürel, Seçil Vural   +24 more
wiley   +1 more source

Female genital lichen sclerosus

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This review provides a comprehensive overview of clinical presentation and emerging evidence supporting a predominantly immune‐mediated pathogenesis characterized by Th1‐skewed inflammation, epithelial dysfunction and progressive fibrosis. Contributory factors including the emerging role for occlusive exposure of susceptible epithelium to urine are ...
Ashley Spencer, Sandra Jerkovic Gulin
wiley   +1 more source

Periodontitis and Adverse Pregnancy Outcomes: Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
This narrative review aims to describe mechanisms linking periodontal diseases in pregnancy with adverse pregnancy outcomes. ABSTRACT Periodontal diseases, including both gingivitis and periodontitis, occur commonly among pregnant individuals. Both gingivitis and periodontitis are associated with adverse pregnancy outcomes (APOs) such as early ...
Gregory C. Valentine, Yiorgos A. Bobetsis, Benjamin C. Shayo, Peter Milgrom, Phoebus N. Madianos   +4 more
wiley   +1 more source

Summarizing the Experiences of Individuals Who Have Obesity or Larger Bodies Seeking Fertility Care: A Scoping Review

Obesity Reviews, EarlyView.
ABSTRACT Females who have larger bodies or obesity may be at an increased risk for experiencing infertility. Problematically, both weight or body size and infertility are stigmatized, harming quality of care. We conducted a scoping review to understand the lived experiences of patients who may be subjected to intersecting stigmas of weight and ...
Brooke J. Hebert, Hanna Randhawa, Virginie Blanchette, Kristi B. Adamo, Angela Alberga, Jean‐Patrice Baillargeon, Marilou Côté, Julia Craig, Ariadne Daniel, Liz Dennett, Nicola Heslehurst, Sarah Nutter, Ian Patton, Helena Piccinini‐Vallis, Ximena Ramos Salas, Katie Wadden, Taniya S. Nagpal   +16 more
wiley   +1 more source

Cytologic Characteristics of the Feline Ovary at Different Sexual Stages

Veterinary Clinical Pathology, EarlyView.
ABSTRACT Background Cytology is a valuable diagnostic tool in veterinary medicine, allowing rapid and minimally invasive diagnosis. However, its application in the reproductive tracts of small animals is limited, primarily used to assess mammary masses and stage the estrous cycle.
Alba Martí, Josep Pastor, David Prandi, Adrià Aguilar‐Catalan, Maria Montserrat Rivera del Alamo   +4 more
wiley   +1 more source

Myths and methodologies: Optimising experimental rigour in heat adaptation research: Menstrual status classification and scheduling approaches

Experimental Physiology, EarlyView.
Abstract Women remain underrepresented in thermal physiology research, particularly within studies examining physiological adaptation to hot environments. Among the limited research that includes female participants, few studies have appropriately classified menstrual status of their participants or rigorously accounted for ovarian hormone influences ...
Jessica A. Mee, Tessa R. Flood
wiley   +1 more source

The interaction between vaginal microbiota, cervical length, and vaginal progesterone treatment for preterm birth risk

, 2017
BACKGROUND: Preterm birth is the primary cause of infant death worldwide. A short cervix in the second trimester of pregnancy is a risk factor for preterm birth. In specific patient cohorts, vaginal progesterone reduces this risk.
Teoh, TG, Smith, A, MacIntyre, DA, Lee, YS, Cacciatore, S, Holmes, E, Kindinger, LM, Marchesi, JR, Nicholson, JK, Bennett, PR   +9 more
core  

Agomelatine ameliorates abortion‐related alterations in rats: Insights from behavioural, biochemical and histological analyses

Experimental Physiology, EarlyView.
Abstract Abortion aetiology is critically linked to increased myometrial contractions and maternal psychological stress. Given the limited efficacy of current therapies such as progesterone, investigating novel therapeutic interventions is essential. Melatonin exerts reproductive benefits.
Mehtap Pervin, Zeynep Dila Oz, Ahmed Sait Bozyil, Orhan Sayin, Husna Batmaz, Serhat Hancer, Salih Burcin Kavak, Nevin Kocaman, Haluk Kelestimur, Emine Kacar   +9 more
wiley   +1 more source