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Cycle regimens for endometrial preparation prior to frozen embryo transfer. [PDF]
Ghobara T, Gelbaya TA, Ayeleke RO.
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Progesterone Luteal Support in Natural Cycles for Unexplained Infertility: A Randomised Controlled Trial (The PiNC Trial). [PDF]
Raperport C +7 more
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Progesterone (PRG) plays a crucial role in the female reproductive system, being the vaginal route the most adequate for its administration, as this drug has an extensive hepatic first pass effect. Nonetheless, vaginal PRG dosage forms originate immediate drug release and requires repeated administrations, which is unpleasant.
Ana Catarina Silva +2 more
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Cervical Pessary and Vaginal Progesterone in Twin Pregnancies With a Short Cervix
Obstetrics & Gynecology, 2016To evaluate cervical pessary as an intervention to prevent preterm birth in twin pregnancies with a short cervix.This was a retrospective cohort study of twin pregnancies managed by a single maternal-fetal medicine practice from 2005 to 2015. We included patients at 28 weeks of gestation or less who were diagnosed with a cervical length less than 20 mm.
Nathan S, Fox +5 more
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American Journal of Obstetrics and Gynecology, 2016
Precocious cervical ripening, as defined by cervical shortening on transvaginal sonography, has prompted a broad evaluation of secondary strategies (such as cerclage, vaginal progesterone, or a cervical pessary) to prevent preterm delivery. However, there is still a lack of direct comparisons between individual treatments or their combinations.We ...
Nathanael Stricker +2 more
exaly +3 more sources
Precocious cervical ripening, as defined by cervical shortening on transvaginal sonography, has prompted a broad evaluation of secondary strategies (such as cerclage, vaginal progesterone, or a cervical pessary) to prevent preterm delivery. However, there is still a lack of direct comparisons between individual treatments or their combinations.We ...
Nathanael Stricker +2 more
exaly +3 more sources
Effect on Endometrial Histology and Pharmacokinetics of Different Dose Regimens of Progesterone Vaginal Pessaries, in Comparison With Progesterone Vaginal Gel and Placebo [PDF]
Which progesterone vaginal pessary dose regimen induces adequate secretory transformation of the endometrium, in comparison with progesterone vaginal gel and placebo?The best secretory transformation of the endometrium was observed during treatment with 400 mg progesterone vaginal pessaries, administered twice daily.Vaginally administered progesterone ...
I J M, Duijkers +6 more
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The Journal of Maternal-Fetal & Neonatal Medicine, 2021
Several studies were published about cervical pessary, with controversial results. These studies demonstrated that the patient follow-up after pessary insertion is very different between the study centers and the number of pessary insertions per center was often
Marcelo Santucci França +10 more
openaire +2 more sources
Several studies were published about cervical pessary, with controversial results. These studies demonstrated that the patient follow-up after pessary insertion is very different between the study centers and the number of pessary insertions per center was often
Marcelo Santucci França +10 more
openaire +2 more sources
Abstract Study question Does the use of pessaries of 400 mg of micronized progesterone provide comparable results as pessaries of 200 mg x2, in terms of progesterone levels? Summary answer The administration of pessaries of Cyclogest®
R Bernabeu, A Bernabeu, J C Castillo
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The Journal of Maternal-Fetal & Neonatal Medicine, 2019
Purpose: To compare the rate of preterm delivery in pregnant women with a short cervical length managed with Arabin cervical pessary and vaginal progesterone versus vaginal progesterone alone.Methods: This was a retrospective cohort study of singletons pregnancies managed in two tertiary medical centers between September 2011 and May 2017.
Yaakov Melcer +7 more
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Purpose: To compare the rate of preterm delivery in pregnant women with a short cervical length managed with Arabin cervical pessary and vaginal progesterone versus vaginal progesterone alone.Methods: This was a retrospective cohort study of singletons pregnancies managed in two tertiary medical centers between September 2011 and May 2017.
Yaakov Melcer +7 more
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AbstractIntroductionPreterm birth is the most common cause of neonatal morbidity and mortality. Women with twin pregnancies and a short cervical length are at high risk for preterm birth. Vaginal progesterone and cervical pessary have been proposed as potential strategies to reduce preterm birth in this high‐risk population.
Vinh Q Dang, Lan N Vuong, Ben W. Mol
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