Results 31 to 40 of about 605 (131)

Prevention of Preterm Birth by Cervical Pessary Combined with Vaginal Progesterone: a Systematic Review and Meta-analysis with Trial Sequential Analysis

Reproductive Sciences, 2022
AbstractThis study was to assess the effectiveness of cervical pessary combined with vaginal progesterone for the prevention of preterm birth (PTB). Ten studies about singleton [five randomized controlled trials (RCTs), vs vaginal progesterone; four cohorts, vs vaginal progesterone; two cohorts, vs cervical cerclage + vaginal progesterone] and two ...
Yanyan Zhuang, Huan Li, Quan Na, Shaowei Yin, Na Li   +4 more
openaire   +2 more sources

The Impact of the Vaginal Microbiome and Microbial Metabolites on HIV Transmission at the Female Reproductive Tract Epithelial Barrier

American Journal of Reproductive Immunology, Volume 96, Issue 2, August 2026.
ABSTRACT Despite major advances in biomedical HIV prevention strategies, almost 50% of the 1.3 million new HIV infections in 2024 occurred in women and girls through heterosexual transmission. Choice in HIV prevention modalities is needed throughout a women's lifespan to increase pre‐exposure prophylaxis uptake; however, there is a paucity of topical ...
Brianna Jesaveluk, Paula Ellenberg, Anna C. Hearps, Gilda Tachedjian   +3 more
wiley   +1 more source

Can universal cervical length screening with vaginal progesterone for a short cervix reduce preterm birth? A systematic review and meta‐analyses

Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 8, Page 1420-1434, August 2026.
Preterm birth is associated with substantial neonatal morbidity and mortality. We evaluated whether universal cervical length screening with ultrasound, followed by progesterone therapy for women with a short cervix, has the potential to reduce the incidence of preterm birth.
Mira Zethelius, Lina Bergman, Ann‐Catrin Ekelund, Cecilie Hongslo Vala, Bo Jacobsson, Pihla Kuusela, Ann Liljegren, Björn Lindkvist, Max Petzold, Petteri Sjögren, Ulla‐Britt Wennerholm, Tove Wikström   +11 more
wiley   +1 more source

A randomised control trial on oral dydrogesterone versus micronized vaginal progesterone pessary for luteal phase support in in vitro fertilization cycles

Journal of Medicine and Life, 2023
This study aimed to evaluate the pregnancy rates, adverse reactions, and medication costs of two luteal phase support regimens: oral dydrogesterone and micronized vaginal progesterone (MVP) pessary in in vitro fertilization cycles. A randomized open-label trial with participants randomly assigned to either 400 mg MVP twice daily or 10 mg dydrogesterone
Ikechebelu, Joseph Ifeanyichukwu, Dim, Cyril Chukwudi, Eleje, George Uchenna, Joe-Ikechebelu, Ngozi, Okpala, Boniface Chukwuneme, Okam, Princeston Chukwuemeka   +5 more
openaire   +2 more sources

The use of topical vaginal estrogens in postpartum women: A systematic review

Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 7, Page 1405-1410, July 2026.
A postpartum reduction in circulating estrogen levels, due to antagonism from elevated prolactin levels, further elevated during breastfeeding, can result in pelvic floor dysfunction, including bladder, bowel and sexual dysfunction, pain and implications for perineal wound healing.
Aysha Waheed, Annika Taithongchai, Dudley Robinson   +2 more
wiley   +1 more source

An Autoethnography of My Experiences of Undergoing Fertility Treatment While Working as an Academic

Gender, Work &Organization, Volume 33, Issue 4, Page 1405-1415, July 2026.
ABSTRACT In this paper, I provide an autoethnographic account of my experiences of undergoing fertility treatment while working in a higher education institution in the United Kingdom. My autoethnographic reflections are situated in the context of neoliberal academia, characterized by high pressures to perform. Despite the prevalence of infertility and
Samantha Wilkinson
wiley   +1 more source

Vaginal Microbiota in Short Cervix Pregnancy: Secondary Analysis of Pessary vs. Progesterone Trial

Diseases
Background/Objectives: Preterm birth (PTB) is a leading cause of neonatal mortality, particularly in women with a short cervix. Vaginal dysbiosis has been associated with increased PTB risk. Progesterone (PR) and Arabin pessary (PE) are commonly used for PTB prevention, but their impact on vaginal microbiome composition is unclear.
Antonio G. Amorim Filho, Roberta C. R. Martins, Lucas A. M. Franco, Juliana V. C. Marinelli, Stela V. Peres, Rossana P. V. Francisco, Mário H. B. Carvalho   +6 more
openaire   +3 more sources

Immunomodulatory Role of Natural Progesterone in Pregnancy: A Review

Journal of Obstetrics and Gynaecology Research, Volume 52, Issue 6, June 2026.
ABSTRACT Aim Pregnancy complications such as miscarriage, preterm birth (PTB), and luteal phase defects (LPD) are significant reproductive health issues globally, with both physical and psychological implications. This review aims to examine the role of natural progesterone in pregnancy‐related disorders, specifically threatened and recurrent ...
Prakash Mehta, Hemant Deshpande, Anjali Deshpande, Reshma Quadros, Shruti Dharmadhikari, Chintan Khandhedia, Gaurav Puppalwar, Amey Mane, Suyog Mehta   +8 more
wiley   +1 more source

Vaginal Progesterone, Oral Progesterone, 17-OHPC, Cerclage, and Pessary for Preventing Preterm Birth in At-Risk Singleton Pregnancies: An Updated Systematic Review and Network Meta-analysis [PDF]

Obstetrical & Gynecological Survey, 2018
(Abstracted from BJOG 2019;126(5):556–567) Around the world, approximately 15 million pregnancies each year end in preterm birth (before 37 weeks' gestation), a major contributor to child morbidity and mortality. To reduce the risk of preterm birth for women at increased risk, interventions include progesterone, cervical cerclage, and ...
A, Jarde, O, Lutsiv, J, Beyene, S D, McDonald   +3 more
openaire   +2 more sources

The association of sociodemographic differences with clinical management following a diagnosis of short cervix

Pregnancy, Volume 2, Issue 3, May 2026.
Abstract Introduction Following diagnosis of a short cervix from 16 through 23 weeks there is considerable variation in clinical practice. We sought to evaluate the association of patient sociodemographic factors with variation in clinical management following diagnosis of a short cervix.
Joseph R. Biggio, Paula L. McGee, George R. Saade, Rebecca G. Clifton, Monica Longo, Sabine Z. Bousleiman, Kelly Clark, William A. Grobman, Heather A. Frey, Suneet P. Chauhan, Lorraine Dugoff, Tracy A. Manuck, Edward K. Chien, Dwight J. Rouse, Hyagriv N. Simhan, M. Sean Esplin, George A. Macones, Matthew K. Hoffman, for the Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal‐Fetal Medicine Units (MFMU) Network   +18 more
wiley   +1 more source