Results 11 to 20 of about 785,437 (225)

Participant experiences with a multipurpose vaginal ring for HIV and pregnancy prevention during a phase 1 clinical trial: learning from users to improve acceptability

Frontiers in Reproductive Health, 2023
IntroductionWith high concurrent global rates of HIV incidence and unintended pregnancy, there is a need to provide options beyond condoms to enable users to simultaneously prevent HIV acquisition and pregnancy.
Mary Kate Shapley-Quinn, Mei Song, Beatrice A. Chen, Beatrice A. Chen, Brid Devlin, Ellen Luecke, Jill Brown, Diana L. Blithe, Sharon L. Achilles, Sharon L. Achilles, Ariane van der Straten, Ariane van der Straten   +11 more
doaj   +1 more source

An isolated vaginal metastasis from intestinal signet ring cell carcinoma: a case report and literature review

BMC Cancer, 2020
Background Isolated vaginal metastases from intestinal signet ring cell carcinoma are extremely rare. There are no reported cases in the domestic or foreign literature. The characteristics of such cases of metastasis remain relatively unknown.
Xiao Dan Zhu, Jin Wang, Qin Han You, Tian An Jiang   +3 more
doaj   +1 more source

Strategies implemented for accurate dispensing of an investigational new drug in a multi-site HIV prevention clinical trial

Contemporary Clinical Trials Communications, 2021
Safe practices for dispensing investigational product (IP) during clinical trials are not standardized and information in this regard is often limited.
Cindy Jacobson, Jayajothi Moodley, Aruna Bhoola, Rebecca Sakwa, Jeeva Moodley, Jasmin Sukdao, Nivriti Hurbans, Bhavna Maharaj, Anushka Naidoo, Melanie Maclachlan, Gift Chareka, Kudzai Hlahla, Mary Chadza   +12 more
doaj   +1 more source

An assessment of the likely acceptability of vaginal microbicides for HIV prevention among women in rural Ghana. [PDF]

, 2012
BACKGROUND: The findings of the CAPRISA tenofovir studies have raised expectations that soon an approved microbicide would be available. However it is in only a limited number of countries in sub-Saharan Africa that the acceptability of microbicides has ...
Tawiah, Charlotte, Charlotte Tawiah, Frank Baiden, Afari-Asiedu Samuel, Martha A Abdulai, Afari-Asiedu, Samuel, Abdulai, Martha A, Abdulai Martha A, Adjei Kwame, Baiden, Frank, Baiden Frank, Samuel Afari-Asiedu, Sam Newton, Adjei, George, Adjei George, Adjei, Kwame, Newton Sam, George Adjei, Tawiah Charlotte, Newton, Sam, Kwame Adjei   +20 more
core   +2 more sources

Safety of a silicone elastomer vaginal ring as potential microbicide delivery method in African women: A Phase 1 randomized trial.

PLoS ONE, 2018
BackgroundWomen in sub-Saharan Africa are in urgent need of female-initiated human immunodeficiency virus (HIV) preventative methods. Vaginal rings are one dosage form in development for delivery of HIV microbicides.
Annaléne Nel, Janine Martins, Linda-Gail Bekker, Gita Ramjee, Gileard Masenga, Helen Rees, Neliëtte van Niekerk   +6 more
doaj   +1 more source

4109 Acceptability of a Tenofovir Disoproxil Fumarate Intravaginal Ring for Human Immunodeficiency Virus Pre-Exposure Prophylaxis Among Sexually Active Women

Journal of Clinical and Translational Science, 2020
OBJECTIVES/GOALS: Vaginal ring delivery of antiretroviral drugs may provide protection against acquisition of HIV-1 when used as pre-exposure prophylaxis.
April Dobkin, Rebecca Barnett, Jessica McWalters, Laurie L. Ray, Lilia Espinoza, Aileen P. McGinn, Jessica M. Atrio, Marla J. Keller   +7 more
doaj   +1 more source

The efficacy of vaginal clindamycin for the treatment of abnormal genital tract flora in pregnancy. [PDF]

, 2003
To assess the efficacy of 2% clindamycin vaginal cream (CVC) to treat bacterial vaginosis (BV) in ...
Sheehan, M, Mandal, D, Jones, BM, Hay, PE, Lamont, RF   +4 more
core   +1 more source

Identifying Low-Frequency Tree-Ring Variation

, 1991
I propose an approach to provide 95% confidence intervals for a chronology of low-frequency tree-ring variation so that a level of significance or importance for trends can be inferred.
Sheppard, Paul R.
core   +4 more sources

Management and outcome of pelvic fracture associated with vaginal injuries: a retrospective study of 25 cases

BMC Musculoskeletal Disorders, 2019
Background Pelvic ring fractures associated with vaginal injuries were rarely reported due to low incidence. The displaced segments of pelvic ring may increase the risk of vaginal injury.
Pengyu Li, Dongsheng Zhou, Baisheng Fu, Wenhao Song, Jinlei Dong   +4 more
doaj   +1 more source

Efficacy and acceptability of the vaginal combination hormone system containing ethinylestradiol and etonogestrel. Literature rewiev [PDF]

Гинекология, 2019
The review focuses on evaluating the effectiveness and acceptability of a vaginal ring and combined oral contraceptives (COC) in a comparative aspect.
Elena A Mezhevitinova, Vera N Prilepskaya   +1 more
doaj   +1 more source