Results 51 to 60 of about 383,903 (316)

Disruption of Gut Microbiota‐Mediated De Novo NAD+ Synthesis Contributes to the Development of Polycystic Ovary Syndrome

open access: yesAdvanced Science, EarlyView.
This study demonstrates that patients with PCOS exhibit altered gut microbial profiles, and FMT from PCOS patients induces PCOS‐like symptoms in mice. Specifically, gut dysbiosis reduces 3‐HAA levels in the context of PCOS. Administration of 3‐HAA to mice alleviates PCOS by promoting de novo NAD+ synthesis.
Ke Chen   +6 more
wiley   +1 more source

Screening of vulvovaginal infections during pregnancy in resource constrained settings: Implications on preterm delivery

open access: yesJournal of Infection and Public Health, 2017
The present study was undertaken to evaluate the efficacy of clinical and microbiological investigations available in limited resource settings for an effective diagnosis of vaginal infections/abnormal vaginal microbiota among pregnant women.
Chaitanya Tellapragada   +5 more
doaj   +1 more source

Pap Test – With or Without Vaginal Smear? [PDF]

open access: yes, 2010
The aim of this study was to evaluate medical and economic justification of vaginal smears as a part of primary screening for cervical carcinoma and its precursors.
Darko Čuržik   +4 more
core   +1 more source

Nociceptive Nerve‐Derived CGRP Exacerbates Uterine Fibrogenesis in Adenomyosis by Promoting CD140b+ CD146+ Fibroblast Differentiation

open access: yesAdvanced Science, EarlyView.
This study investigates adenomyosis fibrosis in relation to nociceptive nerves. Nociceptive nerve‐secreted CGRP promotes RAMP1hi CD140b+ CD146+ fibroblast differentiation into myofibroblasts through ERK activation, causing severe fibrosis. Rimegepant‐induced CGRP/RAMP1 signaling blockade alleviates fibrosis and restores fertility in a mouse model. This
Zi Ye   +11 more
wiley   +1 more source

Hepatic KLF9 Deficiency Inhibits Dehydroepiandrosterone (DHEA)‐Induced Polycystic Ovary Syndrome via Liver‐Ovary Axis

open access: yesAdvanced Science, EarlyView.
The study shows that liver is a previously unrecognized extraovarian organ that plays a key role about androgen homeostasis in the development of DHEA‐induced PCOS. DHEA is the most common precursor of active androgen, such as DHT, and KLF9 is required for the conversion of DHEA to DHT and hepatic KLF9 might be a potential therapeutic target for PCOS ...
Jianli Song   +11 more
wiley   +1 more source

OESTRUS DETECTION IN THE NIGERIAN MONGREL BITCH: APPLICATION OF VAGINAL CYTOLOGY

open access: yesPakistan Veterinary Journal, 2001
Vaginal smears from 45 multiparous Nigerian Mongrel bitches in proestrus (n=10), oestrus (n=22) and pregnancy (n=13) were examined, Differential cell count of exfoliated vaginal epithelial cells showed that the mean percentage of superficial cells was 95
G. D. Mshelia, J. D. Amin and S. U. R. Chaudhari
doaj  

ROLE OF OPPORTUNISTIC MICROFLORA IN MECHANISMS OF DEVELOPMENT OF WOMEN AND MALE INFERTILITY

open access: yesИзвестия высших учебных заведений. Поволжский регион: Медицинские науки, 2020
Background. We made a research on the role of opportunistic microflora in the mechanisms of development of male and female infertilit. The purpose of the research is to study the health of the women and men reproductive system of childbearing age ...
L. V. Kurashvili   +4 more
doaj   +1 more source

Immunolocalization of steroidogenic enzymes in the vaginal mucous of Galea spixii during the estrous cycle. [PDF]

open access: yes, 2017
BackgroundThe synthesis of sex steroids is controlled by several enzymes such as17α-hydroxylase cytochrome P450 (P450c17) catalyzing androgen synthesis and aromatase cytochrome P450 (P450arom) catalyzing estrogen synthesis, both of which must complex ...
Assis Neto, Antônio Chaves de   +5 more
core   +1 more source

In‐Depth Assessment of Cytologic Features in 106 Cervical Papanicolaou Tests of Transgender Male Patients on Testosterone: An Institutional Experience

open access: yesDiagnostic Cytopathology, EarlyView.
ABSTRACT Background There is a decreased cervical cancer screening rate among female to male transgender (FTMTG) patients. Data on the distinct cytologic features present in cervical cytology (CC) of those on testosterone therapy is limited. Methods An 2017–2023 electronic database search identified CC specimens from a cohort of FTMTG patients on ...
Juanita E. Ferreira   +6 more
wiley   +1 more source

CERVIS: Cervical Cancer Early Response Visual Identification System [PDF]

open access: yes, 2019
The goal of CERVIS is to make a substantial, positive impact in the cervical cancer screening space through the development of a minimally invasive, cost effective solution that enables women in low-resource settings to test for cervical cancer on a ...
Hultquist, Claire   +3 more
core   +1 more source

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