Results 91 to 100 of about 12,229,200 (313)

Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis

FEBS Open Bio, EarlyView.
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto, Shiori Sakai, Minori Endo, Terigele, Mizuho Niibori, Taiki Morita, Yu Goto, Arisa Yoshida, Tomohiro Tanaka, Ning Lin, Takahiro Kuchimaru, Hiroyuki Nakamura, Masahiro Inoue, Shinae Kizaka‐Kondoh, Tetsuya Kadonosono   +14 more
wiley   +1 more source

Modeling the Vagueness of Areal Geographic Objects: A Categorization System

ISPRS International Journal of Geo-Information, 2019
Modeling vague objects with indeterminate boundaries has drawn much attention in geographic information science. Because fields and objects are two perspectives in modeling geographic phenomena, this paper investigates the characteristics of vague ...
Yu Liu, Yihong Yuan, Song Gao
doaj   +1 more source

Application of TOPSIS Model Based on Vague Set Entropy in the Evaluation of Groundwater Quality

, 2013
Groundwater quality assessment had important guiding significance on sustainable use of groundwater resources. In order to avoid the subjective judgment on the weight of each index, this article used the Vague set entropy theory to determine the weight ...
Wen-Zhong Yu, D. Tang
semanticscholar   +1 more source

Design and evaluation of FEBS Education and Training Academy module – Integrating generative artificial intelligence into life‐science education

FEBS Open Bio, EarlyView.
Life‐science educators from 14 countries redesigned their own course materials with generative AI in a three‐session, pedagogy‐first FEBS Education and Training Academy workshop built on PICRAT. Among 12 matched respondents, four more reported high confidence in each of five practical domains, and 10 of 13 reported implementing at least one idea ...
Zvonimir Mlinarić, Ali Burak Özkaya
wiley   +1 more source

VAGUENESS AND UNCERTAINTY: A ROUGH SET PERSPECTIVE

Computational Intelligence, 1995
Vagueness and uncertainty have attracted the attention of philosophers and logicians for many years. Recently, AI researchers contributed essentially to this area of research. Fuzzy set theory and the theory of evidence are seemingly the most appealing topics.
openaire   +2 more sources

Ethical Foreground and Background in Adult Educator Work

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Adult educators work in a complex ethical environment. The very act of contributing to the learning of another is fraught with moral overtones. In this paper we consider the ethical dimensions of adult educator practice by distinguishing the ethical features of the context or ‘background’ of practice from the ethical capabilities and decision ...
Steven Hodge, Sonal Nakar
wiley   +1 more source

Embedding regulatory water safety factor into a short-term optimal dispatch model for cascade reservoir operations

Shui kexue jinzhan, 2014
In order to effectively ensure the needs for water safety during the short-term optimal dispatch of cascaded reservoirs,a model for cascade reservoir operation is established.
LI Yong, PEI Weizheng, LI Jia, LI Kefeng, ZHU Ming   +4 more
doaj   +1 more source

Pratiques numériques - vague 8 (ELIPSS 2021)

, 2021
L'enquête "Pratiques numériques" (PN) mesure l'évolution des comportements liés aux technologies de l'information et de la communication (TIC) dans un panel où les répondants ont été équipés d'une tablette tactile connectée.
Sciences Po, Centre de données socio-politiques (CDSP), CNRS
core   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon, Hugues Chabriat, Dominique Hervé, Stéphanie Guey, Sophie Tezenas Du Montcel, Juliette Ortholand   +5 more
wiley   +1 more source