Results 91 to 100 of about 27,618 (287)

Do drugs approved via expedited approval pathways have therapeutic advantages? A systematic review and meta‐analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Regulators use expedited approval pathways to speed market approval and patient access to promising new drugs. However, there is uncertainty about whether these pathways are successful in approving drugs with significant therapeutic advantages. This systematic review aims to examine the safety, effectiveness and cost‐effectiveness of drugs approved via
Ashleigh Hooimeyer   +4 more
wiley   +1 more source

Introduction to Agnosticism on Vagueness

open access: yes, 2005
This paper introduces to the agnostic theories of ...
MORUZZI, SEBASTIANO
core   +1 more source

Extrapolation and pharmacokinetic protocol design optimization for ceftriaxone as an exemplar for the development of antibiotics for children

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Ceftriaxone is a cephalosporin commonly used for the treatment of acute, severe infections; however, there are conflicting data on its disposition properties in children, making it a suitable case study for the evaluation of the appropriateness of extrapolation approaches based on exposure matching principles for paediatric patients and exploring ...
Daniel Valente Neves   +7 more
wiley   +1 more source

Vagueness and Agnosticism

open access: yes, 2005
The paper presents a novel agnostic theory of vagueness based on a margin error principle for ...
MORUZZI, SEBASTIANO
core   +1 more source

Vagueness and Exactiveness in class II, division 2 diagnostics

open access: yesČeská Stomatologie a Praktické Zubní Lékařství, 2020
Introduction, aim: Class II division 2 malocclusion is usually defined by natural informal language (czech, english etc.) as a combination of deep bite and upper central incisor retrusion.
P. Jindra
doaj  

Vagueness Markers in Italian [PDF]

open access: yes, 2022
Moving from a broad socio-pragmatic perspective, this study analyses how speakers of different ages use a class of items and constructions that codify intentional vagueness in Italian.
Ghezzi, Chiara
core  

Unveiling student sentiment dynamics toward AI‐based education through statistical analysis and Monte Carlo simulation

open access: yesBritish Educational Research Journal, EarlyView.
Abstract This study explores the multifaceted dynamics of student sentiment towards artificial intelligence (AI)‐based education by integrating sentiment analysis techniques with statistical methods, including Monte Carlo simulations and decision tree modelling, alongside qualitative grounded theory analysis.
Volkan Duran   +2 more
wiley   +1 more source

A Rational Approach to Soft Rationality

open access: yesPrincipia: An International Journal of Epistemology, 2011
Vagueness is commonly presented as natural language imprecise meaning that is analyzed as borderline cases and formalized in various ways by ‘classical’ theories of vagueness.
Moti Suess
doaj  

Vagueness by degrees

open access: yes, 1997
Book synopsis: Vagueness is currently the subject of vigorous debate in the philosophy of logic and language. Vague terms-such as "tall", "red", "bald", and "tadpole"—have borderline cases (arguably, someone may be neither tall nor not tall); and they ...
Edgington, Dorothy
core  

Storage and manipulation of vague spatial objects using existing GIS functionality [PDF]

open access: yes, 2006
We collect and store data to derive information and make judgments about a world of our interest. Ideally, they should indicate in a unique and certain way which possible world corresponds to the actual world [17].
Dilo, A.   +3 more
core  

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