Results 111 to 120 of about 156,198 (308)
British Journal of Clinical Pharmacology, EarlyView.Regulators use expedited approval pathways to speed market approval and patient access to promising new drugs. However, there is uncertainty about whether these pathways are successful in approving drugs with significant therapeutic advantages. This systematic review aims to examine the safety, effectiveness and cost‐effectiveness of drugs approved via
Ashleigh Hooimeyer +4 more
wiley +1 more source
, 2012 We use princiles of fuzzy logic to develop a general model representing several processes in a system's operation characterized by a degree of vagueness and/or uncertainy.
Voskoglou, Michael Gr.
core +1 more source
British Journal of Clinical Pharmacology, EarlyView.Abstract Aim The quantitative effect of several inhibitory drugs on the development of adverse drug reactions (ADRs) is currently difficult to estimate. Our aim was to identify metabolic pathways, which, when inhibited, increase the risk for certain ADRs, and to use this system to consider comedication at individual level. Methods Data of a prospective
Judith Berres +8 more
wiley +1 more source
An Empirical Comparison of Semantics for Quantified Vague Sentences
ProblemosWe investigate the compositional semantics of vague quantified sentences, focusing on sentences such as “All of the students are tall,” where a non-vague quantifier quantifies into a vague predicate. While much work has been done on vagueness in natural
Alexandre Cremers, Julija Kalvelyte
doaj +1 more source
British Journal of Clinical Pharmacology, EarlyView.Pharmacogenomic (PGx) information has the potential to support the safe and effective use of medicines, yet there is uncertainty about how this information can be best communicated to patients. Summaries of product characteristics (SmPCs) and patient information leaflets (PILs) for all UK‐approved medicines with strong evidence supporting a PGx ...
Parth Narlawar +5 more
wiley +1 more source
Crítica, 2018 In this paper I develop a semantic theory of vagueness that is immune to worries regarding the use of precise mathematical tools. I call this view semantic quietism. This view has the advantage of being clearly compatible with the phenomenon of vagueness.
Ricardo Mena
doaj
British Journal of Clinical Pharmacology, EarlyView.This systematic review identified 112 population pharmacokinetic models of vancomycin in neonates and children. To support rational model selection for model‐informed precision, we developed and applied expert‐driven, transparent criteria that integrate both methodological rigour and clinical relevance.
Zoë Vander Elst +8 more
wiley +1 more source
On the Borders of Vagueness and the Vagueness of Borders [PDF]
, 2018 This article argues that resolutions to the sorites paradox offered by epistemic and supervaluation theories fail to adequately account for vagueness. After explaining the paradox, I examine the epistemic theory defended by Timothy Williamson and discuss
Collins, Rory
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‘Let's talk about the weather’: The activist curriculum and global climate change education
British Educational Research Journal, EarlyView.Abstract Activist movements have garnered significant global attention on a range of sustainability issues, often involving collectives of citizens coming together. Invoked is the idea of citizens informed to act, emerging not from a common‐sense understanding of everyday life, but rather from a deep political understanding of the world—one that is ...
Richard Pountney
wiley +1 more source
Vagueness, credibility, and government policy [PDF]
A discussion of the reasons why it may be in a government agency's--and society's--best interest to be vague about policy objectives. Using the concept of "cheap talk," the author explains that when an agency faces a trade-off between precise and ...
Joseph G. Haubrich
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