British Journal of Pharmacology, EarlyView.Addressing complexity in the study of life sciences through Systems Biology and Systems Medicine has been transformative, making Systems Pharmacology the next logical step. In this review, we focus on physical stimuli, whose potential in pharmacology has been neglected, despite demonstrated therapeutic properties.
Veronica Paparozzi +10 more
wiley +1 more source
The effects of transcutaneous vagus nerve stimulation on evoked potentials and cognitive testing in normal volunteers and epilepsy patients [PDF]
Kristl Vonck +6 more
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Mapping the role of vagus nerve stimulation in post-stroke arm motor recovery. [PDF]
J Neuroeng RehabilAderinto N +5 more
europepmc +1 more source
Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders
British Journal of Pharmacology, EarlyView.Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman +3 more
wiley +1 more source
Vagus nerve stimulation for stroke rehabilitation: Neural substrates, neuromodulatory effects and therapeutic implications [PDF]
Heidi M. Schambra, Seth A. Hays
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Transcutaneous auricular vagus nerve stimulation as an innovative approach for managing perioperative gastrointestinal dysfunction: a narrative review. [PDF]
Front Med (Lausanne)Zhang L +14 more
europepmc +1 more source
Clinical Genetics, EarlyView.We found key differences between tuberous sclerosis patients with TSC1 and TSC2 variants. Patients carrying TSC2 variants had more severe and earlier‐onset symptoms. We also identified two distinct clinical subgroups which follow different disease courses: one characterized by predominant renal involvement and the other by more pronounced neurological ...
Hila Weisblum Neuman +6 more
wiley +1 more source
Analysis of the Outcomes Studied in the Application of Invasive and Non-Invasive Vagus Nerve Stimulation in Clinical and Preclinical Studies Involving Stroke-A Scoping Review. [PDF]
NeuroSciZambetta ML +3 more
europepmc +1 more source
Clinical Obesity, Volume 15, Issue 2, April 2025.Summary Background Bariatric surgery is very effective in long‐term weight management. The present study was undertaken to investigate the short‐term effects of sleeve gastrectomy (SG) and of Roux‐en‐Y gastric bypass (RYGB) on (a) gastrointestinal (GI) motility, that is gastric emptying and oro‐cecal transit time and (b) secretion of regulatory gut ...
Jennifer A. Wilbrink +4 more
wiley +1 more source