Results 251 to 260 of about 771,705 (359)

Piezo2 in Mechanosensory Biology: From Physiological Homeostasis to Disease‐Promoting Mechanisms

Cell Proliferation, EarlyView.
Piezo2 channels are essential mechanotransducers regulating touch, proprioception and visceral mechanosensation across physiological systems, emerging as therapeutic targets for pathological mechanical hypersensitivity and neurogenic disorders. ABSTRACT Piezo2, a mechanically activated ion channel, serves as the key molecular transducer for touch ...
Zhebin Cheng, Zuping Wu, Mengjie Wu, Liang Xie, Qianming Chen   +4 more
wiley   +1 more source

The vagus nerve: a cornerstone for mental health and performance optimization in recreation and elite sports. [PDF]

Front Psychol
Lopez Blanco C, Tyler WJ.
europepmc   +1 more source

An open‐label study on ulotaront's effects on insulin‐glucose regulation in schizophrenia patients with metabolic syndrome and prediabetes: Part I

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Ulotaront is an investigational trace amine‐associated receptor 1 (TAAR1) agonist demonstrated to slow gastric emptying in schizophrenia patients with metabolic syndrome (MetSyn) and prediabetes type 2. Here we evaluate the effects of ulotaront on glucose‐insulin dynamics in schizophrenia patients with MetSyn and prediabetes.
Snezana Milanovic, Robert Lew, Kuangnan Xiong, Emily Casavant, Gerard Galluppi, Yu‐Luan Chen, Yongquan Lai, Manu Chakravarthy, Clay Dehn, Kenneth Koblan, Seth C. Hopkins   +10 more
wiley   +1 more source

The estrous cycle moderates the food and body weight suppressive effects of glucagon‐like peptide‐1 receptor agonism

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Emerging data suggest more young women than men are prescribed weight loss pharmacotherapies targeting the glucagon‐like peptide‐1 receptor (GLP‐1R). However, preclinical literature has largely used male animals to characterize the neural mechanisms underlying the weight loss abilities of GLP‐1R agonists (GLP‐1RAs), highlighting a need ...
Sarah V. Applebey, Allison G. Xiao, Benjamin C. Reiner, Matthew R. Hayes   +3 more
wiley   +1 more source

Evaluating the efficacy and safety of transcutaneous vagus nerve stimulation for systemic lupus erythematosus: a protocol for a systematic review and meta-analysis. [PDF]

BMJ Open
Sun H, Hu H, Bian Z, Liu H, Huang M, Chen S, Wang L, Xiao W, Zhang Y, Fang J, Shao X.   +10 more
europepmc   +1 more source

MRI of the brain is safe in patients implanted with the vagus nerve stimulator

, 2001
Selim R. Benbadis, John Nyhenhuis, William O. Tatum, F. Reed Murtagh, Maria A. Gieron, Fernando Ĺ. Vale   +5 more
openalex   +1 more source

Effectiveness and safety of GLP‐1 receptor agonists in craniopharyngioma patients with obesity: A multicentre real‐world study

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Acquired hypothalamic obesity (aHO) following craniopharyngioma (CP) is a challenging condition with limited therapeutic options. This study aimed to assess the real‐world effectiveness and safety of GLP‐1 RAs in this population. Materials and Methods CranioGLP1 is a retrospective multicentre study including 116 adults with aHO treated ...
Flora Lambert, Emilie Guillon, Blandine Gatta‐Cherifi, CranioGLP1_FORCE Group, Flora Lambert, Emilie Guillon, Hedi Soula, Christine Poitou, Pauline Faucher, Frédérique Albarel, Jean‐Baptiste Bonnet, Anne‐Laure Borel, Marie‐Claude Brindisi, Claire Carette, Delphine Drui, Cédric Fagour, Nicolas Farigon, Bénédicte Gaborit, Blandine Gatta‐Cherifi, Fréderic Illouz, Ryme Jouini‐Bouhamri, Ibrahima Maiga, Emilie Montastier, Héléna Mosbah, Géraldine Vitellius, Olivier Ziegler, Hedi Soula, Christine Poitou, Pauline Faucher   +28 more
wiley   +1 more source

Resting-state functional connectivity changes with microburst vagus nerve stimulation therapy. [PDF]

Epilepsia Open
Allendorfer JB, Nenert R, Shamshiri E, Ranuzzi G, Begnaud J, Verner R, Szaflarski JP, Microburst Study Group.   +7 more
europepmc   +1 more source

Mental stress as a trigger of cardiovascular events: A narrative review

European Journal of Clinical Investigation, EarlyView.
Stress stimulates the prefrontal cortex that in turns activates the limbic system with subsequent activation of the autonomic nervous system. The autonomic nervous system then stimulates the heart, vessels, endocrine and immune systems with a bidirectional communication. These mechanisms increase heart rate and blood pressure, promote vasoconstriction,
Paolo Raggi
wiley   +1 more source