Results 111 to 120 of about 56,717 (347)

Interventional therapies for chronic heart failure: An overview of recent developments

ESC Heart Failure, Volume 12, Issue 2, Page 1081-1094, April 2025.
Abstract Heart failure (HF), the final manifestation of most cardiovascular diseases, has become a major global health concern, affecting millions of individuals. Despite basic drug treatments, patients present with high morbidity and mortality rates. However, recent advancements in interventional therapy have shown promising results in improving the ...
Bingchen Guo, Si Shi, Yutong Guo, Jie Xiong, Bo Wang, Zengxiang Dong, Dianyu Gao, Yingfeng Tu   +7 more
wiley   +1 more source

Vagus nerve stimulation boosts the drive to work for rewards

Nature Communications, 2020
The vagus nerve transmits signals between the gut and the brain thereby tuning motivated behavior to physiological needs. Here, the authors show that acute non-invasive stimulation of the vagus nerve via the ear enhances the invigoration of effort for ...
Monja P. Neuser, Vanessa Teckentrup, Anne Kühnel, Manfred Hallschmid, Martin Walter, Nils B. Kroemer   +5 more
doaj   +1 more source

Phenotype characterization of heart failure with preserved ejection fraction in medical device and surgical trials

ESC Heart Failure, EarlyView.
This systematic review identified 24 clinical trials of medical device and surgical interventions for HFpEF, with 16 demonstrating at least safety and feasibility, but little evidence of long‐term benefit. Phenotype‐based responses suggest that certain interventions may benefit specific HFpEF subgroups, yet most trials suffered from heterogeneous ...
Kurdo Araz, Francesco Fioretti, Sara Ladak, Mohammed Obaidan, Javed Butler, Aamir Hameed   +5 more
wiley   +1 more source

Transcutaneous Auricular Vagus Nerve Stimulation-Paired Rehabilitation for Oromotor Feeding Problems in Newborns: An Open-Label Pilot Study

Frontiers in Human Neuroscience, 2020
Neonates born premature or who suffer brain injury at birth often have oral feeding dysfunction and do not meet oral intake requirements needed for discharge. Low oral intake volumes result in extended stays in the hospital (>2 months) and can lead to
Bashar W. Badran, Dorothea D. Jenkins, Daniel Cook, Sean Thompson, Morgan Dancy, William H. DeVries, Georgia Mappin, Philipp Summers, Marom Bikson, Mark S. George, Mark S. George   +10 more
doaj   +1 more source

Practical and clinical utility of non-invasive vagus nerve stimulation (nVNS) for the acute treatment of migraine. A post hoc analysis of the randomized, sham-controlled, double-blind PRESTO trial [PDF]

, 2018
Background: The PRESTO study of non-invasive vagus nerve stimulation (nVNS; gammaCore®) featured key primary and secondary end points recommended by the International Headache Society to provide Class I evidence that for patients with an episodic ...
Ambrosini, A, Andersson, A, Anna, Ambrosini, Aurilia, C, Baldi, Mg, Barbanti, P, Bernetti, L, Bianchi, M, Bitetto, V, Cevoli, S, Chiariello, Ga, Chiarugi, A, Corbelli, I, Cortelli, P, Cristina, Tassorelli, De Cesaris, F, De Icco, R, De Martino, P, de Tommaso, M, Di Maro, D., Egeo, G, Eric, Liebler, Fofi, L, Gai, A, Geppetti, P, Giulia, Pierangeli, Govone, F, Grazzi, L, Licia GrazziEmail author,, Liebler, E, Lupi, C, Marin, J, Marina de Tommaso,, Marone, I, Martelletti, P, Martinelli, D, Masuzzo, F, McClure, C, Negro, A, Padovan, Am, Paola, Sarchielli, Paolo, Martelletti, Perrotta, A, Pierangeli, G, Pierangelo, Geppetti, Puma, Sl, Rainero, I, Rainero, Innocenzo, Ricci, K, Romoli, M, Rubino, E, Sances, G, Sarchielli, P, Simoni, S, Spitzer, L, Tassorelli C, Piero Barbanti PRESTO Study Group., Terlizzi, R, Thackeray, L, Torrieri, Mc, Vacca, A, Vecchio, E, Verzina, A   +61 more
core   +2 more sources

Radiofrequency thermocoagulation for the treatment of refractory focal status epilepticus

Epileptic Disorders, EarlyView.
Abstract This case study reports the first documented use of stereoelectroencephalography (SEEG)‐guided radiofrequency thermocoagulation (RFTC) to treat refractory status epilepticus (RSE). A 33‐year‐old woman with drug‐resistant epilepsy and recurrent RSE underwent SEEG to define her epileptogenic zone.
Odile Feys, Julia Makhalova, Thomas Manners, José‐David Herrera‐García, Romain Carron, Fabrice Bartolomei   +5 more
wiley   +1 more source

Seminars in epileptology: Presurgical epilepsy evaluation

Epileptic Disorders, EarlyView.
Abstract All patients with drug‐resistant seizures benefit from a comprehensive evaluation to confirm their seizure diagnosis and explore surgical treatment options. This seminar in epileptology discusses advancements in the field and provides specific didactic material to create an active working knowledge for the care of patients with focal drug ...
Stephan Schuele, Robyn M. Busch, Birgit Frauscher, Vadym Gnatkovsky, Hajo Hamer, Lara Jehi, Andres Kanner, Georgia Ramantani, Theodor Rüber, Andreas Schulze‐Bonhage, Rainer Surges, Lara Wadi   +11 more
wiley   +1 more source

Gut‐microbiota‐brain Axis and post‐traumatic epilepsy

Epilepsia Open, EarlyView.
Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley   +1 more source

Effects of anti-inflammatory vagus nerve stimulation on the cerebral microcirculation in endotoxinemic rats

Journal of Neuroinflammation, 2012
Background In sepsis syndromes the severity of the inflammation triggers microvascular dysfunction and early organ failure. We studied the effects of anti-inflammatory vagus nerve stimulation on the cerebral microcirculatory integrity in an endotoxinemic
Mihaylova Stanka, Killian Anke, Mayer Konstantin, Pullamsetti Soni, Schermuly Ralph, Rosengarten Bernhard   +5 more
doaj   +1 more source

A Flexible Platform for Biofeedback-driven Control and Personalization of Electrical Nerve Stimulation Therapy [PDF]

, 2015
Electrical vagus nerve stimulation is a treatment alternative for many epileptic and depressed patients whose symptoms are not well managed with pharmaceutical therapy.
Irazoqui, Pedro, John, Simon W. M., Otto, Kevin J., Qing, Kurt Y., Ward, Matthew P., Worth, Robert M.   +5 more
core   +1 more source