Results 231 to 240 of about 197,837 (340)

Pulmonary arterial mechanoreceptors mediate sustained sympathoexcitation during high altitude hypoxia in humans

Experimental Physiology, EarlyView.
Abstract Sympathetic nervous system activation is a hallmark of high‐altitude hypoxia, yet the afferent mechanisms remain incompletely defined. We examined the relative contributions of pulmonary arterial mechanoreceptors and carotid chemoreceptors – two excitatory pathways co‐activated by hypoxia – to sustained sympathoexcitation at altitude.
Michiel T. Ewalts, Lydia L. Simpson, Jack S. Talbot, Elliott J. Jenkins, Travis D. Gibbons, Connor A. Howe, Lauren E. Maier, Emily R. Vanden Berg, Alex M. Williams, Philip N. Ainslie, Samuel J. Oliver, Craig D. Steinback, Mike Stembridge, Jonathan P. Moore   +13 more
wiley   +1 more source

Transcutaneous vagus nerve stimulation in breast cancer: a neuroimmune model to improve quality of life. [PDF]

Front Oncol
Do M, Tyler WJ.
europepmc   +1 more source

Cardiac remodelling in type 2 diabetes: Pathophysiological mechanisms and opportunities for multiscale computational modelling and simulation

The Journal of Physiology, EarlyView.
Abstract figure legend Overview of multiscale cardiac remodelling in type 2 diabetes and how to model and simulate these changes using a human‐based, multiscale computational framework. Cardiac remodelling in type 2 diabetes occurs at ionic channel, protein, cellular, tissue and whole‐organ level, affecting the electrophysiological function, mechanical
Ambre Bertrand, Jakub Tomek, Blanca Rodriguez   +2 more
wiley   +1 more source

Transcutaneous auricular vagus nerve stimulation may improve cognitive deficits in neuropsychiatric diseases-a systematic review. [PDF]

Front Aging Neurosci
Jost ST, Happe F, Koenig J, Dafsari HS.
europepmc   +1 more source

Prediabetic cardiomyopathy is attenuated by hypothalamic PVN oxytocin neuron activation

The Journal of Physiology, EarlyView.
Abstract figure legend A long‐term high‐fat, high‐fructose diet induces prediabetes with insulin resistance, hyperinsulinaemia, elevated triglycerides and metabolic‐associated steatotic liver disease (MASLD) in male rats. Animals developed prediabetic cardiomyopathy characterized by diastolic dysfunction, interstitial fibrosis and tachycardia ...
Anna Nilsson, Joan Escobar, Kira Kuraoka, Ian Venter, Cielo A. Carnate, Matthew W. Kay, David Mendelowitz, Kathryn J. Schunke   +7 more
wiley   +1 more source

Transcutaneous auricular vagus nerve stimulation for major depressive disorder: current evidence and future research directions. [PDF]

Front Psychiatry
Sun J, Gao D, Zhang J, Liu H, Zhou Y, Ma C, Zhang X, Liu S, Zhao J, Hao C, Xiao X.   +10 more
europepmc   +1 more source

Pulmonary arterial mechanoreceptors modulate exercise‐induced sympathetic activation in healthy humans during moderate‐intensity hypoxic exercise

The Journal of Physiology, EarlyView.
Abstract figure legend This randomized cross‐over trial (N = 12) addressed the hypothesis that selective reduction of pulmonary arterial pressure (i.e. manipulation of pulmonary arterial mechanoreceptor activation) during hypoxic exercise would reduce sympathetic outflow (muscle sympathetic nerve activity (MSNA)) in healthy humans.
Michiel T. Ewalts, Thomas D. Griffiths, Andrew J. M. Douglas, Elliott J. Jenkins, Guto Wyn Hughes, Craig D. Steinback, Lydia L. Simpson, Samuel J. Oliver, Mike Stembridge, Jonathan P. Moore   +9 more
wiley   +1 more source

Non-Invasive Vagus Nerve Stimulation in Cluster Headache: A Clinical Practice Guideline. [PDF]

Pain Pract
Goadsby PJ, Feoktistov A, Anitescu M, Day M, Staats P.   +4 more
europepmc   +1 more source

Noninvasive vagus nerve stimulation to target gait impairment in Parkinson's disease [PDF]

, 2019
Baker, Mark R., Hunter, Heather, Morris, Rosie, Rochester, Lynn, Taylor, John-Paul, Yarnall, Alison J.   +5 more
core   +1 more source

Modelling the time‐resolved modulations of cardiac activity in rats: A study on pharmacological autonomic stimulation

The Journal of Physiology, EarlyView.
Abstract figure legend Time‐resolved estimation of cardiac rhythmicity parameters. A pipeline is shown for the estimation of the fluctuating cardiac parameters, based on the Poincaré plot. The Poincaré plot illustrates the successive changes in interbeat intervals (IBI).
Diego Candia‐Rivera, Sofia Carrion‐Falgarona, Fabrizio de Vico Fallani, Mario Chavez   +3 more
wiley   +1 more source