Results 21 to 30 of about 9,445,211 (322)

Validation issues in educational data mining:the case of HTML-Tutor and iHelp [PDF]

, 2010
Validation is one of the key aspects in data mining and even more so in educational data mining (EDM) owing to the nature of the data. In this chapter, a brief overview of validation in the context of EDM is given and a case study is presented. The field
Cocea, Mihaela, Weibelzahl, Stephan
core   +1 more source

A novel human tau knock-in mouse model reveals interaction of Abeta and human tau under progressing cerebral amyloidosis in 5xFAD mice

Alzheimer’s Research & Therapy, 2023
Background Hyperphosphorylation and intraneuronal aggregation of the microtubule-associated protein tau is a major pathological hallmark of Alzheimer’s disease (AD) brain.
Susan Barendrecht, An Schreurs, Stefanie Geissler, Victor Sabanov, Victoria Ilse, Vera Rieckmann, Rico Eichentopf, Anja Künemund, Benjamin Hietel, Sebastian Wussow, Katrin Hoffmann, Kerstin Körber-Ferl, Ravi Pandey, Gregory W. Carter, Hans-Ulrich Demuth, Max Holzer, Steffen Roßner, Stephan Schilling, Christoph Preuss, Detlef Balschun, Holger Cynis   +20 more
doaj   +1 more source

Synthesis and structure–activity relationships of pyrazole-based inhibitors of meprin α and β

Journal of Enzyme Inhibition and Medicinal Chemistry, 2023
Targeting metalloproteinases has been in the focus of drug design for a long time. However, meprin α and β emerged as potential drug targets just recently and are linked to several diseases with different pathological background.
Kathrin Tan, Christian Jäger, Stefanie Geissler, Dagmar Schlenzig, Mirko Buchholz, Daniel Ramsbeck   +5 more
doaj   +1 more source

Human activity recognition making use of long short-term memory techniques [PDF]

, 2019
The optimisation and validation of a classifiers performance when applied to real world problems is not always effectively shown. In much of the literature describing the application of artificial neural network architectures to Human Activity ...
Shenfield, Alex, Wainwright, Richard
core   +1 more source

Development and validation of a geriatric depression screening scale: a preliminary report.

Journal of Psychiatric Research, 1982
A new Geriatric Depression Scale (GDS) designed specifically for rating depression in the elderly was tested for reliability and validity and compared with the Hamilton Rating Scale for Depression (HRS-D) and the Zung Self-Rating Depression Scale (SDS ...
J. Yesavage, T. Brink, Terence L. Rose, Owen Lum, V. Huang, M. Adey, V. Leirer   +6 more
semanticscholar   +1 more source

Temporal evolution of generalization during learning in linear networks [PDF]

, 1991
We study generalization in a simple framework of feedforward linear networks with n inputs and n outputs, trained from examples by gradient descent on the usual quadratic error function.
Baldi, Pierre, Chauvin, Yves
core   +1 more source

Automated validation of genetic variants from large databases: ensuring that variant references refer to the same genomic locations

Bioinform., 2011
Summary: Accurate annotations of genomic variants are necessary to achieve full-genome clinical interpretations that are scientifically sound and medically relevant.
Mark Y. Tong, C. Cassa, Isaac S. Kohane
semanticscholar   +1 more source

Silhouettes: a graphical aid to the interpretation and validation of cluster analysis

, 1987
A new graphical display is proposed for partitioning techniques. Each cluster is represented by a so-called silhouette, which is based on the comparison of its tightness and separation.
P. Rousseeuw
semanticscholar   +1 more source

Validation of the theoretical domains framework for use in behaviour change and implementation research

Implementation Science, 2012
BackgroundAn integrative theoretical framework, developed for cross-disciplinary implementation and other behaviour change research, has been applied across a wide range of clinical situations.
J. Cane, Denise A. O’Connor, S. Michie
semanticscholar   +1 more source

Model-driven transformation and validation of adaptive educational hypermedia using CAVIAr [PDF]

, 2010
Authoring of Adaptive Educational Hypermedia is a complex activity requiring the combination of a range of design and validation techniques.We demonstrate how Adaptive Educational Hypermedia can be transformed into CAVIAr courseware validation models ...
Melia, Mark, Pahl, Claus
core   +2 more sources