Results 31 to 40 of about 3,926,210 (300)

FY-3G Satellite Instruments and Precipitation Products: First Report of China’s Fengyun Rainfall Mission In-Orbit

open access: yesJournal of Remote Sensing, 2023
Precipitation is one of the most important parameters in Earth system but is hard to measure. China began to develop satellites dedicated to precipitation measurements in the second generation of the FengYun polar-orbiting meteorological satellite ...
Peng Zhang   +16 more
doaj   +1 more source

A novel human tau knock-in mouse model reveals interaction of Abeta and human tau under progressing cerebral amyloidosis in 5xFAD mice

open access: yesAlzheimer’s Research & Therapy, 2023
Background Hyperphosphorylation and intraneuronal aggregation of the microtubule-associated protein tau is a major pathological hallmark of Alzheimer’s disease (AD) brain.
Susan Barendrecht   +20 more
doaj   +1 more source

Evidence for Enhanced Efficacy of Passive Immunotherapy against Beta-Amyloid in CD33-Negative 5xFAD Mice

open access: yesBiomolecules, 2022
Passive immunotherapy is a very promising approach for the treatment of Alzheimer’s disease (AD). Among the different antibodies under development, those targeting post-translationally modified Aβ peptides might combine efficient reduction in beta ...
Kathrin Gnoth   +10 more
doaj   +1 more source

Synthesis and structure–activity relationships of pyrazole-based inhibitors of meprin α and β

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2023
Targeting metalloproteinases has been in the focus of drug design for a long time. However, meprin α and β emerged as potential drug targets just recently and are linked to several diseases with different pathological background.
Kathrin Tan   +5 more
doaj   +1 more source

Once Validated, Always Validated? [PDF]

open access: yesThe Journals of Gerontology Series B: Psychological Sciences and Social Sciences, 2007
YOU need a brief measure, say, of stress, or social resources, or functional status. You find one that not only seems to address the conceptual issues about which you are concerned, but for which information on validity and reliability have also been published. Moreover, it has been used frequently, and its name is well recognized.
openaire   +2 more sources

Pedagogical validation of courseware [PDF]

open access: yes, 2007
A lack of pedagogy in courseware can lead to learner rejection. It is therefore vital that pedagogy is a central concern of courseware construction. Courseware validation allows the course creator to specify the pedagogical rules and principles that ...
Pahl, Claus   +3 more
core   +2 more sources

Who checks the checkers? four validation tools applied to eight atomic resolution structures

open access: yes, 1998
Eight protein crystal structures, which have been refined against X-ray diffraction data extending to atomic resolution, 1.2 Å or better, were inspected using four different validation tools, PROCHECK, PROVE, SQUID and WHATCHECK.
EU-3D-Validation-Network
core   +1 more source

CNN models trained in cross-validation

open access: yes, 2023
Models trained in 10-fold cross-validation for pleural thickening and scoliosis classification using different pre-trained CNN models.
Naoaki ONO (16974216)
core   +1 more source

Sustainable intensification of oil palm production through integration with other crops: a review☆

open access: yesOilseeds and fats, crops and lipids
Unsustainable monoculture systems practices, driven by global demand for agricultural commodities like palm oil, contribute to deforestation, biodiversity loss, and soil degradation, compromising livelihoods and environmental health. With increasing land
Munévar-Martínez Daniel Eduardo   +3 more
doaj   +1 more source

Image Navigation for FY-4A Lightning Mapping Imager

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2021
Navigation of images from lightning mapping instruments in geostationary orbits is very important for data applications. However, few scientific peer-reviewed papers have been reported, except a few works in the prelaunch tests.
Jing Wang   +7 more
doaj   +1 more source

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