Results 171 to 180 of about 52,085,429 (356)

A validated algorithm to identify recurrence of bladder cancer: a register-based study in Denmark

Clinical Epidemiology, 2018
Linda Aagaard Rasmussen,1 Henry Jensen,1 Line Flytkjær Virgilsen,1 Jørgen Bjerggaard Jensen,2,3 Peter Vedsted1 1Research Centre for Cancer Diagnosis in Primary Care (CaP), Research Unit for General Practice, Department of Public Health ...
Rasmussen LA, Jensen H, Virgilsen LF, Jensen JB, Vedsted P   +4 more
doaj  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Validation of contralateral premolars as the substrate for endodontic comparison studies

, 2018
AIM: To use micro-CT technology and metrology software to validate the use of contralateral premolars as samples in endodontic comparison studies by comparing them before and after canal instrumentation with one instrumentation system.
Sunde, Pia Titterud, Haugen, Håvard Jostein, Johnsen, Gaute Floer   +2 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

QMCA Development and Validation Studies

Assessment and Validation studies for ...
Philip Cola, Joann Quinn, Casey Miller, Melissa Cooper   +3 more
core  

PENGEMBANGAN KARTU SEBAGAI MEDIA PEMBELAJARAN ILMU PENGETAHUAN SOSIAL SISWA KELAS VII SMP DENGAN MATERI PROSES ENDOGEN DAN EKSOGEN

, 2021
This study aimed to: 1) develop cards for Social Studies learning media for the topic of endogenic and exogenic processes for Grade VII of the junior high school (JHS), and 2) investigate the appropriateness of the cards media based on the assessment by ...
Seto, Danar Aji
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Dependence module of the MINI plus adapted for sugar dependence: psychometric properties Módulo de dependência do MINI plus adaptado para dependência de açúcar: propriedades psicométricas

Psicologia: Reflexão e Crítica, 2013
This study aimed to analyze the factorial structure and the scale of measurement of the items for dependence of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) adapted for sugar consumption in order to verify if the structural ...
Marco Aurélio Camargo da Rosa, Cristiano Mauro Assis Gomes, Neusa Sica da Rocha, Felix Henrique Paim Kessler, Sonia Maria Blauth de Slavutzky, Efigênia Ferreira e Ferreira, Flavio Pechansky   +6 more
doaj  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Validation of questionnaire used in epidemiological blood pressure studies

Open Medicine, 2012
Stawińska-Witoszyńska Barbara, Kowalska Małgorzata, Krzyżaniak Alicja, Krzywińska-Wiewiorowska Małgorzata, Krzych Łukasz   +4 more
doaj   +1 more source