Results 61 to 70 of about 52,085,429 (356)

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

Internal construct validity of the Brazilian version of a tool for assessing the population’s knowledge of human papillomavirus

Revista Brasileira de Epidemiologia
: Objective: To verify the internal construct validity of the Brazilian Portuguese version of a tool for measuring the general population’s knowledge of human papillomavirus (HPV).
Fabiana Schuelter Trevisol, Rodrigo Dias Nunes, Gabriel Oscar Cremona Parma, André Luciano Manoel, Clávison Martinelli Zapelini, Daisson José Trevisol, Jefferson Traebert   +6 more
doaj   +1 more source

Evaluation of the Interobserver Agreement of the Fraser and Blake & McBryde Classifications for Floating Knee

Revista Brasileira de Ortopedia, 2021
Objective To evaluate the interobserver agreement of two classifications for floating knee: Fraser and Blake & McBryde. Method Thirty-two observers, subdivided according to the degree of titration (26 resident physicians and 6 orthopedic physicians ...
Jonatas Brito Alencar Neto, Ernane Bruno Osório Neto, Clodoaldo José Duarte de Souza, Pedro Henrique Messias da Rocha, Maria Luzete Costa Cavalcante, Márcio Bezerra Gadelha Lopes   +5 more
doaj   +2 more sources

Persuasive Gaming: From Theory Based Design to Validation and Back. An Introduction [PDF]

, 2021
This chapter offers a multifaceted reflection on persuasive gaming divided into three pillars: persuasiveness, design, and validation. The first section on persuasiveness is a critical review of previous and current persuasive gaming theory and analysis.
Kors, Martijn, Jansz, Jeroen, Jacobs, Ruud, Raessens, Joost, Schouten, Ben, ICON - Media and Performance Studies, LS Mediatheorie, de la Hera, Teresa   +7 more
core   +1 more source

Validation studies for population-based intervention coverage indicators: design, analysis, and interpretation

Journal of Global Health, 2018
Background Population-based intervention coverage indicators are widely used to track country and program progress in improving health and to evaluate health programs.
M. Munos, A. Blanc, Emily Carter, T. Eisele, Steve Gesuale, Joanne Katz, Tanya Marchant, C. Stanton, H. Campbell   +8 more
semanticscholar   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke, Christian Thomas, Michael C. Frühwald, Pascal D. Johann, Martin Hasselblatt   +4 more
wiley   +1 more source

Knowledge based environment to support product design validation [PDF]

, 2012
A knowledge-based environment to support product design validation of refresh projects (projects with minor changes in comparison with previous ones) has been developed.
Molyneaux, M., V. Santamaría, Moliner, F., Brunner, B., D. Tanjore, Ewers, Paul, Ahmed Al-Ashaab, A. Doultsinou, P. Ewers, Knight, G., E. Martínez, Tanjore, D., G. Knight, B. Brunner, F. Moliner, Santamaría, V., M. Molyneaux, Al-Ashaab, Ahmed, Doultsinou, Athanasia, Martínez, E.   +19 more
core   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási, Bernadett Borbála Huszti, Gábor Barna, Marko Kavcic, Janez Jazbec, Lennart Lenk, Vera Münch, Sophia Polychronopoulou, Ágnes Márk, Maria Thastrup, Lüder H. Meyer, Kjeld Schmiegelow, Cornelia Eckert, Christina Halsey, Dániel J. Erdélyi   +14 more
wiley   +1 more source

Revising the comprehensive feeding practices questionnaire used in planning preventive overweight, obesity, and underweight programs for 2–5-year-old children

International Journal of Preventive Medicine, 2019
Background: Overweight, obesity, and underweight are common child health problems in Iran. Child-feeding practices are one of the major factors affecting children's weight through eating behavior and dietary intake.
Mina Minaie, Khadijeh Mirzaei, Ramin Heshmat, Ariyo Movahedi, Ahmadreza Dorosty Motlagh, Mahboubeh Parsaeian, Soori Soghra Raghebi, Abolghasem Djazayery   +7 more
doaj   +1 more source

Pilot3 D5.2 - Verification and validation report [PDF]

, 2022
The deliverable provides the outcomes from the verification and validation activities carried during the course of work package 5 of the Pilot3 project, and according to the verification and validation plan defined in deliverable D5.1 (Pilot3 Consortium,
De Falco, P., Kuljanin, J., Delgado, L., Schultz, R., Prats, X., De Homdedeu, J., Argerich, C., Montlaur, A., Valput, D.   +8 more
core