Results 71 to 80 of about 52,085,429 (356)

Validity and reliability in quantitative studies [PDF]

Evidence Based Nursing, 2015
Evidence-based practice includes, in part, implementation of the findings of well-conducted quality research studies. So being able to critique quantitative research is an important skill for nurses. Consideration must be given not only to the results of the study but also the rigour of the research. Rigour refers to the extent to which the researchers
Roberta, Heale, Alison, Twycross
openaire   +2 more sources

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

Added predictive value of high-throughput molecular data to clinical data, and its validation [PDF]

, 2010
Hundreds of ''molecular signatures'' have been proposed in the literature to predict patient outcome in clinical settings from high-dimensional data, many of which eventually failed to get validated. Validation of such molecular research findings is thus
Sauerbrei, Willi, Boulesteix, Anne-Laure
core   +1 more source

Study on the Validity of Pancreaticoduodenectomy in the Elderly [PDF]

Anticancer Research, 2017
Pancreaticoduodenectomy (PD) is still the only curative treatment for periampullary cancer. Confirming the outcomes of PD in elderly patients is important as the aging population continues to grow.We analyzed 340 patients with periampullary cancer who underwent PD, dividing them into three groups by age: group A: aged 64 years or younger, n=115; group ...
Yasuro, Futagawa, Masaru, Kanehira, Kenei, Furukawa, Hiroaki, Kitamura, Seiya, Yoshida, Teruyuki, Usuba, Takeyuki, Misawa, Yuichi, Ishida, Tomoyoshi, Okamoto, Katsuhiko, Yanaga   +9 more
openaire   +2 more sources

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

Comparison of a short version of the Food Frequency Questionnaire with its long version - a cross-sectional analysis in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)

São Paulo Medical Journal
CONTEXT AND OBJECTIVE: The food frequency questionnaire (FFQ) is the preferred instrument for obtaining dietary information in epidemiological studies.
Livia Welter Mannato, Taisa Sabrina Silva Pereira, Gustavo Velasquez-Melendez, Letícia de Oliveira Cardoso, Isabela Martins Benseñor, Maria del Carmen Bisi Molina   +5 more
doaj   +1 more source

Profiling medical school learning environments in Malaysia: a validation study of the Johns Hopkins Learning Environment Scale [PDF]

Journal of Educational Evaluation for Health Professions, 2015
Purpose: While a strong learning environment is critical to medical student education, the assessment of medical school learning environments has confounded researchers.
Sean Tackett, Hamidah Abu Bakar, Nicole A. Shilkofski, Niamh Coady, Krishna Rampal, Scott Wright   +5 more
doaj   +1 more source

Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies [PDF]

, 2002
BACKGROUND: The age-specific relevance of blood pressure to cause-specific mortality is best assessed by collaborative meta-analysis of individual participant data from the separate prospective studies.
Lewington, S, Qizilbash, N, Prospective Studies Collaboration Team, Lewington, Sarah, Collins, R, Peto, Richard, Jamrozik, Konrad D., Prospective Studies Collaboration, Peto, R, Clarke, Robert, Clarke, R, Qizilbash, Nawab, Collins, Rory   +12 more
core   +1 more source

Evaluation of the 24-Hour Recall as a Reference Instrument for Calibrating Other Self-Report Instruments in Nutritional Cohort Studies: Evidence From the Validation Studies Pooling Project

American Journal of Epidemiology, 2017
Calibrating dietary self-report instruments is recommended as a way to adjust for measurement error when estimating diet-disease associations. Because biomarkers available for calibration are limited, most investigators use self-reports (e.g., 24-hour ...
L. Freedman, J. Commins, W. Willett, L. Tinker, D. Spiegelman, D. Rhodes, N. Potischman, M. Neuhouser, A. Moshfegh, V. Kipnis, D. Baer, L. Arab, R. Prentice, A. Subar   +13 more
semanticscholar   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source