Results 71 to 80 of about 4,269,345 (275)

Translation, Cross-Cultural Adaptation, and Psychometric Validation of the Authentic Nurse Leadership Questionnaire for the Portuguese Context: A Methodological Study

Nursing Reports
Background: Authentic leadership is characterized by the authenticity and self-awareness of the leader, who acts with transparency and promotes positive outcomes in clinical practice and team management.
Pedro Lucas, Ana Gaspar, Paulo Cruchinho, Mafalda Inácio, Ana Rita Figueiredo, Luísa Dias, Paula Agostinho, João Oliveira, Marie Giordano-Mulligan, Elisabete Nunes, Patrícia Costa   +10 more
doaj   +1 more source

Content and Face Validity of the Mackey Childbirth Satisfaction Rating Scale Questionnaire Crossculturally Adapted to Brazilian Portuguese [PDF]

Revista Brasileira de Ginecologia e Obstetrícia, 2019
Objective The aim of this study was to determine the content and face validity of the Mackey Childbirth Satisfaction Rating Scale (MCSRS) questionnaire cross-culturally adapted to Brazilian Portuguese.
Fernanda Lopes, Nelson Carvas Júnior, Mary Uchiyama Nakamura, Roseli Mieko Yamamoto Nomura   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Development and Validation of an Educational Tool on Hypodermoclysis for Palliative Care Professionals

Nursing Reports
Background/Objectives: Hypodermoclysis has gained increasing recognition as a safe, effective, and minimally invasive method for administering medication and fluids in palliative care.
Maria Vanessa Tomé Bandeira de Sousa, Carlos Laranjeira, José Mateus Pires, Isabela Melo Bonfim, Luís Carlos Carvalho Graça, Karla Maria Carneiro Rolim, Lara Anisia Menezes Bonates, Régia Christina Moura Barbosa Castro, Ana Fátima Carvalho Fernandes   +8 more
doaj   +1 more source

Tradução e validação do The five part questionnaire for identifying hypermobility para a língua portuguesa do Brasil Translation into Brazilian Portuguese and validation of the five-part questionnaire for identifying hypermobility

Revista Brasileira de Reumatologia, 2011
INTRODUÇÃO: A hipermobilidade articular (HA) é uma condição clínica hereditária em que há aumento da elasticidade articular em movimentos passivos. Na população em geral, a frequência varia entre 10% e 20%, podendo ser estimada por métodos específicos ...
Daniela Aparecida de Moraes, Carlos Alberto Baptista, José Alexandre Souza Crippa, Paulo Louzada-Junior   +3 more
doaj   +1 more source

Cancer biomarker development from basic science to clinical practice [PDF]

, 2018
The amount of published literature on biomarkers has exponentially increased over the last two decades. Cancer biomarkers are molecules that are either part of tumour cells or secreted by tumour cells.
Ali, Asif, Ali, Zafar, Oien, Karin A., Yousafzai, Yasar Mehmood   +3 more
core  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source