Results 141 to 150 of about 252,061 (302)

Test of Gross Motor Development : Expert Validity, confirmatory validity and internal consistence

open access: yesRevista Brasileira de Cineantropometria e Desempenho Humano, 2008
The Test of Gross Motor Development (TGMD-2) is an instrument used to evaluate children’s level of motordevelopment. The objective of this study was to translate and verify the clarity and pertinence of the TGMD-2 items by expertsand the confirmatory ...
Nadia Cristina Valentini   +5 more
doaj  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

A data-driven latent variable approach to validating the research domain criteria framework

open access: yesNature Communications
Despite the widespread use of the Research Domain Criteria (RDoC) framework in psychiatry and neuroscience, recent studies suggest that the RDoC is insufficiently specific or excessively broad relative to the underlying brain circuitry it seeks to ...
S. K. L. Quah   +9 more
doaj   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Understanding ‘stuckness’ : Descriptions and interpretations of how EFL speakers and a native speaker co-manage talk-in-interaction [PDF]

open access: yes, 2006
Taking turns in keeping the talk going is a co-managed accomplishment. When the talk does not flow, the moment is noticeable and accountable. I am proposing the use of a new term, ‘stuckness’, as an organizational concept which describes certain moments ...
Myers, Greg, Nakamura, Ian
core  

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Addressing Gaps in Educational Evaluation: A Comprehensive Meta-Analysis

open access: yesMimbar Ilmu
Educational evaluation plays a crucial role in ensuring the effectiveness of the learning process. However, various studies indicate gaps in the implementation of effective evaluation methods, such as the lack of a holistic approach and limited valid ...
Yoga Dwi Arianda   +2 more
doaj   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

The business case for equal opportunities : equality, equity and egalitarianism [PDF]

open access: yes, 2001
The research project reported in this thesis concerned the business case for equal opportunity in the workplace. The project comprised three distinct but related studies: 1.
O'Malley, Siobhan, O'Malley, S.
core  

Modeling Political Discourse in Indonesia’s 2024 Election Using Unsupervised Machine Learning

open access: yesJurnal Sisfokom
The 2024 General Election in Indonesia has generated a large volume of diverse and unstructured digital political discourse, necessitating a machine learning-based analytical approach for efficient, objective, and scalable data processing.
Malikhatul Ibriza   +3 more
doaj   +1 more source

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