Comparative evaluation of artificial intelligence-assisted literature search tools for identifying clinically meaningful evidence in cardiology. [PDF]
Di Febo R +8 more
europepmc +1 more source
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
Perspective (Institute for Christian Studies)
The laudatio for Dianne Bergsma by James Olthuis appeared in Perspective 48, no. 2 (Sept 2014) http://hdl.handle.net/10756/332755Master of Worldview Studies: To New York and Beyond -- Student Achievements -- Enhancing Global Access to ICS Research ...
Guthrie-McNaughton, Isabella +8 more
core
Editorial: Community series in biomarker discovery and therapeutic innovations in genito-urinary cancer management, volume II. [PDF]
Roviello G, Zhu Y.
europepmc +1 more source
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph +7 more
wiley +1 more source
Editorial: Microbial solutions for soil health and remediation: from natural diversity to engineered communities. [PDF]
Zhuo R, Zhang X.
europepmc +1 more source
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
Editorial: Emerging targeted and immunotherapeutic strategies in oncology: from solid tumors to hematologic malignancies. [PDF]
Muresan XM, Tigu AB, Roman A, Romani A.
europepmc +1 more source
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source

