Results 111 to 120 of about 252,061 (302)

Cultural adaptation, validation and evaluation of the psychometric properties of Childbirth Experience Questionnaire version 2.0 in the Spanish context

BMC Pregnancy and Childbirth
Background Several instruments have been designed to assess the childbirth experience. The Childbirth Experience Questionnaire (CEQ) is one of the most widely used tools.
Elisabet Machín-Martín, Héctor González-de la Torre, Haridian Bordón-Reyes, Julia Jeppesen-Gutiérrez, Alicia Martín-Martínez   +4 more
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

A Re-Examination of a Previous Study Relating to Topical Body Formulations: Validating Gene Expression Transcription at Multiple Time Points, and Protein Expression and Translation in an Ex Vivo Model

Cosmetics
Introduction: This study was conducted to question the findings of a prior study published in Journal of Drugs in Dermatology (JDD) in September 2023, which reported that a topical firming and toning body lotion (FTB—SkinMedica®, Allergan Aesthetics, an AbbVie Company, Irvine, CA, USA) upregulated several genes in a UV-irradiated 3D full-thickness ...
Alan D. Widgerow, Mary E. Ziegler, Faiza Shafiq   +2 more
openaire   +2 more sources

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Using accreditation of prior experiential learning (apel) to replace a practice placement: A controversial option?

, 2007
The Accreditation of Prior Experiential Learning (APEL) is established in higher education, but there are no studies on its use in occupational therapy.
Tempest, S, Cordingley, K, Craik, C
core   +1 more source

Development of Emerging Infectious Diseases Preventive Health Behavior (EID-PHB) Scale and Validation of the Complex Models

Journal of Multidisciplinary Healthcare
Wee Kyung Lee, Sung Rae Shin Department of Nursing, Sahmyook University, Seoul, South KoreaCorrespondence: Sung Rae Shin, Department of Nursing, Sahmyook University, 815 Hwarang-ro, Nowon-gu, Seoul, 01795, South Korea, Tel +82-2-3399-1588, Fax +82-2-3399-
Lee WK, Shin SR
doaj  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

PENGEMBANGAN MEDIA PEMBELAJARAN INTERAKTIF IPS BERBASIS ADOBE FLASH CS 6 UNTUK SISWA SMPLB/B (TUNARUNGU) POKOK BAHASAN USAHA MANUSIA DALAM MEMENUHI KEBUTUHAN

, 2016
This study aimed to: 1) produce Social Studies interactive learning media based on Adobe Flash Cs 6 in accordance with the needs of students with hearing impairment for the topic of Human Efforts to Satisfy Needs; 2) investigate the appropriateness of ...
Gunawan, Gilang Rony
core  

Understandings of evidence-based practice within a group of practising Educational Psychologists. [PDF]

, 2012
The drive for professionals to become more evidence-based has resulted in a climate of greater scrutiny and accountability. However the notion of evidence-based practice as a positive force in the work of practitioners is contested, particularly within ...
Urquhart, Callum
core  

Development and Evaluation of the Bvee Kit for Teaching Circle Topics: A Validity and Usability Study in Form 2 Mathematics

International Journal of Information and Education Technology
In the 21st century, the success of a country depends on ideas and the ability to build a scientific and innovative society. Essentially, the enhancement of teaching aids is as important as the development and innovation in the education field.
openaire   +1 more source