Results 81 to 90 of about 252,061 (302)

Development and validation of instruments to assess content knowledge and topic specific pedagogical content knowledge of teachers of organic chemistry

, 2013
In 1986, Shulman described Pedagogical Content Knowledge (PCK), as the transformation of Content Knowledge into various forms which help students to understand the concepts.
Vokwana, Nonkanyiso Queen, Nonkanyiso Queen Vokwana   +1 more
core  

Automated test data generation on the analyses of feature models: A metamorphic testing approach [PDF]

, 2010
This is the post-print version of the Article. The official published version can be accessed from the links below. Copyright © 2010 IEEE.A Feature Model (FM) is a compact representation of all the products of a software product line.
Sergio Segura, Segura, S, Benavides, D, Antonio Ruiz-Cortés, Ruiz Cortés, Antonio, Segura Rueda, Sergio, Robert M. Hierons, Benavides Cuevas, David Felipe, Ruiz-Cortés, A, Hierons, Robert M., David Benavides, Hierons, RM   +11 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

DO PLACEBO BASED VALIDATION STANDARDS MIMIC REAL BATCH PRODUCTS BEHAVIOUR? CASE STUDIES

, 2011
peer reviewedAnalytical methods validation is a mandatory step to evaluate the ability of developed methods to provide accurate results for their routine application.
Talbi, M., Ph. Hubert, A. Bouabidi, M. Talbi, Bourichi, H., Bouklouze, A., M. El Guezzar, El Guezzar, M., H. Bourichi, M. El Karbane, Bouabidi, A., El Karbane, M., E. Rozet, Ziemons, Eric, A. Bouklouze, Hubert, Philippe, E. Ziemons, Rozet, Eric   +17 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

PENGEMBANGAN BLOG INTERAKTIF SEBAGAI SUMBER BELAJAR IPS SMP KELAS VII DENGAN MATERI KEGIATAN POKOK EKONOMI

, 2016
This study aimed to: 1) develop a blog as a Social Studies learning resource for GradeVII of the junior high school (JHS) for the topic of primary economic activities, and 2)investigate the appropriateness of the blog for the topic of primary economic ...
Hidayanto, Wahid
core  

Escalas de avaliação para Terapia Ocupacional no Brasil

Revista de Terapia Ocupacional da Universidade de São Paulo, 2010
A produção científica relativa às intervenções e avaliações em Terapia Ocupacional têm avançado. Instrumentos de avaliação são cada vez mais utilizados para avaliar resultados de intervenções nos Estados Unidos, Canadá, Austrália e em países da Europa ...
Giseli de Fátima dos Santos Chaves, Alexandra Martini de Oliveira, Orestes Vicente Forlenza, Paula Villela Nunes   +3 more
doaj   +1 more source

Detecting Conversation Topics in Recruitment Calls of African American Participants to the All of Us Research Program Using Machine Learning: Model Development and Validation Study (Preprint)

JMIR Formative Research
BACKGROUND Advancements in science and technology can exacerbate health disparities, particularly when there is a lack of diversity in clinical research, which limits the benefits of innovations for underrepresented communities.
Priscilla Pemu, Michael Prude, Atuarra McCaslin, Elizabeth Ojemakinde, Christopher Awad, Kelechi Igwe, Anny Rodriguez, Jasmine Foriest, Muhammed Idris   +8 more
openaire   +3 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source