Results 111 to 120 of about 4,984,553 (349)
On The Difficulty of Validating Molecular Generative Models Realistically: A Case Study on Public and Proprietary Data [PDF]
, 2023 Koichi Handa +4 more
openalex +1 more source
Definition, implementation and validation of energy code smells: an exploratory study on an embedded system [PDF]
, 2013 Optimizing software in terms of energy efficiency is one of the challenges that both research and industry will have to face in the next few years.We consider energy efficiency as a software product quality characteristic, to be improved through the ...
Ardito, Luca +3 more
core
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Not-So-Classical Measurement Errors: A Validation Study of Homescan [PDF]
We report results from a validation study of Nielsen Homescan data. We use data from a large grocery chain to match thousands of individual transactions that were recorded by both the retailer (at the store) and the Nielsen Homescan panelist (athome ...
Aviv Nevoy, Ephraim Leibtag, Liran Einav
core
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
FEBS Letters, EarlyView.At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
Validating the ukpds 82 risk equations to contemporary outcomes studies in type 2 diabetes [PDF]
, 2014 DeAna G. Grant, V. Foos, P McEwan
openalex +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
DiagnosticsObjective: This ex vivo diagnostic study aimed to externally validate a freely accessible AI-based model for caries detection, classification, localisation and segmentation using an independent image dataset.
Elisabeth Frenkel +7 more
doaj +1 more source