Results 141 to 150 of about 4,984,553 (349)

Validation and Improvement of the Saga Fall Risk Model: A Multicenter Retrospective Observational Study

open access: yesClinical Interventions in Aging
Masaki Tago,1 Risa Hirata,1 Naoko E Katsuki,1 Eiji Nakatani,2 Midori Tokushima,1 Tomoyo Nishi,1 Hitomi Shimada,3 Shizuka Yaita,1 Chihiro Saito,4 Kaori Amari,5 Kazuya Kurogi,6 Yoshimasa Oda,7 Kiyoshi Shikino,8,9 Maiko Ono,10 Mariko Yoshimura,11 Shun ...
Tago M   +19 more
doaj  

Concordance between two methods in measuring treatment adherence in patients with type 2 diabetes

open access: yesPatient Preference and Adherence, 2016
Flora López-Simarro,1 Carlos Brotons,2 Irene Moral,2 Alba Aguado-Jodar,3 Cèlia Cols-Sagarra,1 Sònia Miravet-Jiménez11Primary Health Care Center Martorell, Institut Català de la Salut, Barcelona, Spain; 2Research Unit ...
López-Simarro F   +5 more
doaj  

Ki-67 proliferation index to further stratify invasive breast cancer molecular subtypes: Northern African comparative cohort-study with external TCGA-BRCA and metabric validation

open access: gold, 2022
Laila Akhouayri   +6 more
openalex   +1 more source

Preseason Lower Extremity Functional Test Scores Are Not Associated With Lower Quadrant Injury - A Validation Study With Normative Data on 395 Division III Athletes

open access: yes, 2018
Background: Preseason performance on the lower extremity functional test (LEFT), a timed series of agility drills, has been previously reported to be associated with future risk of lower quadrant (LQ = low back and lower extremities) injury in Division ...
Brumitt, Jason   +5 more
core  

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

mRNA expression of ER, PR, HER2 and Ki67 are concordant to central ihc and predict clinical outcome: A validation study from the ABCSG-6 biomarker cohort [PDF]

open access: hybrid, 2018
Martin Filipits   +13 more
openalex   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

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