Results 221 to 230 of about 4,984,553 (349)

Exoscopic Visualization for Transorbital Surgery: Preliminary Anatomical and Clinical Validation Study. [PDF]

J Clin Med
Corrivetti F, de Notaris M, Corvino S, Piazza A, Porto E, Leo S, Cavaliere C, De Simone M, Iaconetta G, Kong DS.   +9 more
europepmc   +1 more source

TREX1, a predator for treating MSI‐H tumors?

Molecular Oncology, EarlyView.
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya, Joséphine Deneft, Marc Van den Eynde   +2 more
wiley   +1 more source

Predicting Shunt-Dependency After Aneurysmal Subarachnoid Hemorrhage: A Multicenter Validation Study. [PDF]

J Clin Med
Said M, Wipplinger C, Cattaneo A, Wipplinger TM, Kunze E, Dömer P, Helgers S, Jabbarli R, Woitzik J.   +8 more
europepmc   +1 more source

Development and Validation of RP–HPLC Method for Estimation of Curcumin from Nanocochleates and Its Application in in–vivo Pharmacokinetic Study

, 2020
Sameer Nadaf, Suresh G. Killedar
openalex   +2 more sources

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Ultrasonographic Assessment of Posterior Shoulder Capsule Thickness in Baseball Pitchers: A Validation Study. [PDF]

Sports Health
Paul RW, Long SS, Coladonato C, Ahrens J, Hoback A, Buchheit P, Rauch J, Ciccotti MG, Cohen SB, Erickson BJ, Thomas SJ.   +10 more
europepmc   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

The WONE Index as a Multidimensional Assessment of Stress Resilience: A Development and Validation Study.

J Med Internet Res
Roos LG, Gilliland D, Julian K, Misra R.
europepmc   +1 more source

Explainable machine learning model of coronary artery disease combined with diabetes: development and validation study. [PDF]

Front Cardiovasc Med
Wang X, Wang S, Liu X, Xie R, Liang S, Wang B, Zhang Y.   +6 more
europepmc   +1 more source

Posterior pole teleophthalmology based on a smartphone adapter: a clinical validation study in an emergency department [PDF]

F González Márquez, J L García Garmendia, L Castillón Torre, F J Hernández Martínez, J M Campos Domínguez, S Andrades Segura   +5 more
openalex   +1 more source