Results 101 to 110 of about 4,179,049 (359)

Pharmacological effects of osimertinib on a chicken chorioallantoic membrane xenograft model with the EGFR exon‐19‐deleted advanced NSCLC mutation

open access: yesFEBS Open Bio, EarlyView.
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy   +14 more
wiley   +1 more source

Validez de las escalas de afecto positivo y negativo (PANAS) en niños (Validity Of The Positive And Negative Affect Schedule (PANAS) In Children) [PDF]

open access: yesLiberabit, 2015
Resumen El presente estudio tiene como objetivo evaluar las propiedades psicométricas de las escalas PANAS (afecto positivo y afecto negativo), su validez convergente con una medida de resiliencia y fiabilidad en una muestra de 194 niños, de ambos sexos,
Norma Ivonne González Arratia López Fuentes   +1 more
doaj  

The Danish Psychosocial Work Environment Questionnaire (DPQ): Development, content, reliability and validity

open access: yesScandinavian Journal of Work, Environment & Health, 2019
OBJECTIVES: The aim of this study was to describe the development and the content of the Danish Psychosocial Work Environment Questionnaire (DPQ) and to test its reliability and validity.
Thomas Clausen   +7 more
doaj   +1 more source

On Hopf's Lemma and the Strong Maximum Principle

open access: yes, 2005
In this paper we consider Hopf's Lemma and the Strong Maximum Principle for supersolutions to a class of non elliptic equations. In particular we prove a sufficient condition for the validity of Hopf's Lemma and of the Strong Maximum Principle and we ...
Bertone, S.   +2 more
core   +2 more sources

A non‐fluorescent immunohistochemistry method for measuring autophagy flux using MAP1LC3/LC3 and SQSTM1 as core markers

open access: yesFEBS Open Bio, EarlyView.
We introduce an immunohistochemistry method to measure autophagy flux, highlighting the active degradation and recycling of cellular waste. This cost‐effective approach uses tissue samples to track key markers like LC3 and SQSTM1, revealing how cells maintain health or respond to diseases such as cancer. It bridges the gap between research and clinical
Shahla Shojaei   +6 more
wiley   +1 more source

Concentration inequalities of the cross-validation estimator for Empirical Risk Minimiser [PDF]

open access: yesarXiv, 2010
In this article, we derive concentration inequalities for the cross-validation estimate of the generalization error for empirical risk minimizers. In the general setting, we prove sanity-check bounds in the spirit of \cite{KR99} \textquotedblleft\textit{bounds showing that the worst-case error of this estimate is not much worse that of training error ...
arxiv  

Validation of the Croatian Version of the Sense of Coherence 29-Item Scale in Croatian Nurses

open access: yesSlovenian Journal of Public Health, 2020
The aim of the study was to validate the Croatian version of the Sense of Coherence 29-item instrument (SOC-29) within a nursing population.
Smrekar Martina   +3 more
doaj   +1 more source

Range of validity of transport equations

open access: yes, 2005
Transport equations can be derived from quantum field theory assuming a loss of information about the details of the initial state and a gradient expansion. While the latter can be systematically improved, the assumption about a memory loss is in general
Berges, Jurgen, Borsanyi, Szabolcs
core   +2 more sources

Transcultural Ethnic Validity Model and Intracultural Competence [PDF]

open access: yes, 2012
To be a psychosocially competent person, each of us has to have both an internal and an external perspective on our self and our culture, a transcultural ethnic validity perspective.
Tyler, Forrest B.
core   +3 more sources

An enzyme‐linked immunosorbent assay (ELISA)‐based activity assay for AMP‐activated protein kinase (AMPK)

open access: yesFEBS Open Bio, EarlyView.
Measuring AMP‐activated protein kinase (AMPK) activity in vitro is crucial for testing AMPK activators or inhibitors with therapeutic potential. Here, we report an enzyme‐linked immunosorbent assay (ELISA)‐based AMPK activity assay with simple steps and high sensitivity, which offers a simple, robust, and cost‐effective alternative to traditional ...
Trezze P. Nguyen, Shangze Lyu, Yang Liu
wiley   +1 more source

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