Results 101 to 110 of about 2,730,603 (357)

The MSA Atrophy Index (MSA‐AI): An Imaging Marker for Diagnosis and Clinical Progression in Multiple System Atrophy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Reliable biomarkers are essential for tracking disease progression and advancing treatments for multiple system atrophy (MSA). In this study, we propose the MSA Atrophy Index (MSA‐AI), a novel composite volumetric measure to distinguish MSA from related disorders and monitor disease progression. Methods Seventeen participants with an
Paula Trujillo   +11 more
wiley   +1 more source

Physical literacy evaluation of primary school students in indonesia: validity and reliability analysis of PL-C Quest instrument with rasch model

open access: yesRetos: Nuevas Tendencias en Educación Física, Deportes y Recreación
Introduction. Good physical literacy is important for students to support a better life. therefore it is necessary to evaluate it. Objectives. This study aimed to evaluate the level of physical literacy of primary school students in Indonesia with a ...
Ahmad Chaeroni   +2 more
doaj   +1 more source

Performance of Composite Endpoints Defining Progression Independent of Relapse Activity in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The characteristics and utility of composite progression independent of relapse activity (cPIRA; worsening on the Expanded Disability Status Scale [EDSS], or 9‐Hole Peg Test, or Timed 25‐Foot Walk Test) were evaluated as an endpoint in relapsing multiple sclerosis (RMS) trials using the ENSEMBLE (NCT03085810) and pooled OPERA I/II ...
Ludwig Kappos   +11 more
wiley   +1 more source

Strategies, practices, and challenges in enhancing quality assurance in qualitative biomedical research: A multi-method study protocol [PDF]

open access: yesJournal of Research Development in Nursing and Midwifery
Background: The qualitative research paradigm is crucial for understanding complex human phenomena, making credibility essential for its findings. Challenges in applying quality assessment criteria and promoting responsible practices in biomedical ...
Hamidreza Khankeh   +4 more
doaj  

Continuous Monitoring of Bladder Dysfunction in People With Multiple Sclerosis: Wearables for the Bladder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Bladder dysfunction affects over 85% of people with multiple sclerosis (PwMS), yet current assessment methods are limited to periodic in‐clinic evaluations or subjective patient reports, failing to capture real‐world symptom fluctuations.
Valerie J. Block   +8 more
wiley   +1 more source

The Youth Risk Index: psychometrics, predicting the initiation of early adolescent substance use, and the breadth of liability detected

open access: yesFrontiers in Child and Adolescent Psychiatry
IntroductionOver the last two decades, drug use epidemics have occurred across the world, including in countries with well-funded services for treatment and recovery, underscoring the need to bolster primary prevention.
Ty A. Ridenour   +12 more
doaj   +1 more source

Early Intensive Versus Escalation Approach: Ten‐Year Impact on Disability in Relapsing Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the long‐term impact of early intensive treatment (EIT) versus escalation (ESC) strategies using high‐efficacy disease‐modifying therapies (HE‐DMTs) on disability progression in relapsing multiple sclerosis (RMS). Methods This observational study included 4878 RMS patients from the Italian Multiple Sclerosis Register ...
Pietro Iaffaldano   +47 more
wiley   +1 more source

Psychometric models of emerging adulthood: an evaluation in a Chilean university sample

open access: yesFrontiers in Psychology
This study analyzed three models of the Inventory of the Dimensions of Emerging Adulthood (IDEA): the original by Reifman et al., the version based on Arnett’s proposals, and the abbreviated version by Crocetti et al.
Paula Boero   +2 more
doaj   +1 more source

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