Results 81 to 90 of about 2,124,694 (305)
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Issues of validity and reliability in qualitative research [PDF]
, 2015 Evaluating the quality of research is essential if findings are to be utilised in practice and incorporated into care delivery. In a previous article we explored ‘bias’ across research designs and outlined strategies to minimise bias.1 The aim of this ...
Noble, H +3 more
core +1 more source
Quantitative data collection and study validity
, 2013 The quality of data collection methods selected and the integrity of the data collected are integral to the; quantitative success of a study. This chapter focuses on data collection and study validity. After reading the chapter, readers should be able to
Osborne, Sonya, Schneider, Zevia
core +1 more source
Abstract Validity underscores all aspects of testing, from conceptualizing the targeted construct to evaluating the consequences of test score interpretations and uses. Validation entails constructing and evaluating coherent arguments for and against test score interpretations and uses, as well as the resulting consequences.
Lane Suzanne, Marion Scott F.
openaire +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Screening for Chronic Obstructive Pulmonary Disease: Validity and Reliability of a Portable Device in Non-Specialized Healthcare Settings. [PDF]
, 2016 The underdiagnosis of chronic obstructive pulmonary disease (COPD) could be improved through screening using portable devices simpler than conventional spirometers in specific healthcare settings to reach a higher percentage of the at-risk population ...
Fernández Villar, José Alberto +4 more
core +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Reliability and Validity of the Readiness of Parenthood Scale [PDF]
, 2007 Purpose:To examine the reliability and validity of the readiness of parenthood scale for adolescent males and females. The readiness of parenthood scale consists of 2 sub-scales.
SASAKI, Ayako, 佐々木, 綾子
core
Validity of age at menarche self-reported in adulthood [PDF]
, 2006 Objective: To test the validity of age at menarche self-reported in adulthood and examine whether socioeconomic position, education, experience of gynaecological events and psychological symptoms influence the accuracy of recall.Design: Prospective birth
Hardy, R +15 more
core +1 more source