Results 71 to 80 of about 4,681,406 (303)

Toward Personalized Orthopedic Care: Validation of a Smart Knee Brace

open access: yesDigital Biomarkers
Introduction: Wearable technology offers a promising solution to advance current rehabilitation strategies for post-operative orthopedic care. The aim of this study was to determine the level of agreement and concurrent validity of a smart knee brace ...
Annah McPherson   +2 more
doaj   +1 more source

eLiteracy or information literacy : which concept should we prefer? [PDF]

open access: yes, 2005
To give a comparative analysis of the validity of the concepts of eLiteracy (eL) and Information Literacy (IL). eLiteracy and Information Literacy are different but mutually compatible concepts with validity within specific contexts. By defining concepts
Joint, Nicholas
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Development and Psychometric Properties of a Questionnaire to Assess Iranian Women’s Sexual Self-disclosure [PDF]

open access: yesمراقبت پرستاری و مامایی ابن سینا
Background and Objective: Sexual self-disclosure plays an important role in couples' sexual performance and satisfaction. It is necessary to have a valid, reliable tool to measure this variable. A review of the literature shows that there is no tool with
Raziyeh Maasoumi   +2 more
doaj  

The Bayesian One-Sample t-Test Supersedes Correlation Analysis as a Test of Validity

open access: yesEuropean Journal of Psychology Open
: Introduction: The validity of measurement, which refers to how accurately tools measure what they are intended to measure, is essential in science. Researchers rely on statistical approaches to test the validity of their measures.
Phivos Phylactou   +2 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Validity proof of Lazard's method for CAD construction

open access: yes, 2017
In 1994 Lazard proposed an improved method for cylindrical algebraic decomposition (CAD). The method comprised a simplified projection operation together with a generalized cell lifting (that is, stack construction) technique. For the proof of the method'
McCallum, Scott   +2 more
core   +1 more source

Use of a 3-item short-form version of the Barthel Index for use in stroke: systematic review and external validation [PDF]

open access: yes, 2017
Background and Purpose—There may be a potential to reduce the number of items assessed in the Barthel Index (BI), and shortened versions of the BI have been described.
Ali, Myzoon   +5 more
core   +2 more sources

Home - About - Disclaimer - Privacy