Results 101 to 110 of about 2,124,694 (305)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

A Weighted Sum Validity Function for Clustering with a Hybrid Niching Genetic Algorithm [PDF]

, 2005
Clustering is inherently a difficult problem, both with respect to the construction of adequate objective functions as well as to the optimization of the objective functions.
Liu, X, Zhang, Leishi, Weiguo Sheng, Stephen Swift, Xiaohui Liu, Zhang, L, Sheng, Weiguo, Sheng, W, Swift, S, Swift, S., Leishi Zhang, Liu, Xiaohui   +11 more
core   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Reliability and validity of the Mentalization Questionnaire in a potentially depressed group of Chinese college students

Frontiers in Psychiatry
PurposeMentalization, as a core psychosocial function, not only encompasses emotional regulation but also involves the perception and comprehension of one’s own and others’ emotional states, constituting a crucial capacity for establishing adaptive ...
Xin Huang, Zemin Zhou, Guang Yang, Jiao Liu, Xuan Li, Xuemei Li   +5 more
doaj   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Turkish Adaptation of Mothers’ Cultural Beliefs About Weaning Scale: A Validity and Reliability Study

Lokman Hekim Dergisi
Objective: The aim of this study was to determine the validity and reliability of the ‘Cultural Beliefs about Weaning Scale’ among breastfeeding women in the Turkish population.Method: The data of the methodologically designed study were collected by ...
Aytül Hadımlı, Emine Serap Çağan, Sevil Güner, Aysun Ekşioğlu   +3 more
doaj   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Validity challenge in GenAI models: Evaluating the validity of content generated by text-to-image models in the context of social studies education [PDF]

Generative artificial intelligence (GenAI) models have led to many positive changes in educational settings; however, the validity of the content they produce remains a significant topic of academic discussion.
Okan Yetişensoy
core   +2 more sources

Investigating plant awareness: Methodologies, challenges and possibilities

Plants, People, Planet
Societal Impact Statement Plants are crucial for sustaining life on Earth, and understanding human relationships to plants is key to ensuring that the role of plants is recognized in biology research.
Irma Brkovic, Dawn Sanders, Eva Nyberg
doaj   +1 more source