Results 121 to 130 of about 4,605,214 (355)

Measuring the Validity of Clustering Validation Datasets

open access: yesIEEE Transactions on Pattern Analysis and Machine Intelligence
Clustering techniques are often validated using benchmark datasets where class labels are used as ground-truth clusters. However, depending on the datasets, class labels may not align with the actual data clusters, and such misalignment hampers accurate validation.
Hyeon Jeon   +5 more
openaire   +3 more sources

The rs10191329 Risk Allele Is Associated With Pronounced Retinal Layer Atrophy in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate whether the rs10191329 risk allele in the DYSF–ZNF638 locus, which is implicated in central nervous system resilience rather than immune‐mediated pathology, is associated with retinal layer thinning, a biomarker of neuroaxonal damage in relapsing multiple sclerosis (RMS). Methods From a prospective observational study,
Gabriel Bsteh   +22 more
wiley   +1 more source

Continuity equation and local gauge invariance for the N3LO nuclear Energy Density Functionals

open access: yes, 2011
Background: The next-to-next-to-next-to-leading order (N3LO) nuclear energy density functional extends the standard Skyrme functional with new terms depending on higher-order derivatives of densities, introduced to gain better precision in the nuclear ...
A. Messiah   +10 more
core   +1 more source

Long‐Term Evaluation of Givinostat in Duchenne Muscular Dystrophy, and Natural History Comparisons

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives This ongoing, open‐label extension study is evaluating the long‐term safety, tolerability, and efficacy of givinostat, a Class I and II histone deacetylase inhibitor, in patients with Duchenne muscular dystrophy (DMD). Methods The recruited patients completed one of two prior clinical studies (one Phase 2 and one Phase 3 [EPIDYS ...
Craig M. McDonald   +74 more
wiley   +1 more source

Turkish version of the Tilburg Frailty Indicator

open access: yesClinical Interventions in Aging, 2019
Yildiray Topcu, Fatih Tufan, Cihan Kilic Department of Geriatrics, Istanbul School of Medicine, Istanbul University, Istanbul, Turkey Background: Recently frailty has drawn significant interest as an important predictor of several clinically relevant ...
Topcu Y, Tufan F, Kilic C
doaj  

Durability of Response to B‐Cell Maturation Antigen‐Directed mRNA Cell Therapy in Myasthenia Gravis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We report the 12‐month follow‐up outcomes from a Phase 2 clinical trial (NCT04146051) evaluating Descartes‐08, a BCMA‐directed RNA chimeric antigen receptor T‐cell (rCAR‐T) therapy for refractory generalized myasthenia gravis (MG).
Nizar Chahin   +10 more
wiley   +1 more source

Translation, Adaptation and Validation of Referral Systems Assessment and Monitoring Toolkit for the Family Physicians Program in Iran

open access: yesJournal of Mazandaran University of Medical Sciences, 2019
Background and purpose: Studies on the function of referral system in Iran had not covered all aspects and structures of the referral system. This could be due to lack of an appropriate tool that could investigate referral system in Iran.
Samad Rouhani   +2 more
doaj  

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