Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
In article the mathematical and statistical analysis of the quality of a test on a subject "Limits. Derivatives" is carried out. The most important characteristics at quality check of a test are reliability and validity.
Larisa V. Limanova, Lidiya A. Muratova
doaj
ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung +7 more
wiley +1 more source
High-quality changes of the pedagogical test "linear algebra, analytical geometry"
In this article according to the classical theory characteristics of validity and discriminative of the pedagogical test "Linear Algebra, Analytical Geometry" of a course of the higher mathematics of Samara State Technical University were estimated ...
Lidiya A. Muratova
doaj
Development and Validation of an Instrument for Clinical Evaluation of Nursing Teachers (Student Form) in Ahvaz Jundishapur University of Medical Sciences Iran [PDF]
Background & Objective: It is necessary for a correct evaluation to use valid instruments prepared exactly according to the study population and special field This study aimed to determine valid and reliable criteria for clinical evaluation of nursing ...
Fahimeh Sabeti +3 more
doaj
Background Accurate assessment of acetabular defects and designing precise and feasible surgical plans are essential for positive outcomes of hip revision arthroplasty. Additive manufacturing (AM) is a novel technique to print physical object models.
Jingwei Zhang +5 more
doaj +1 more source
Direct evaluation of the isotope effect within the framework of density functional theory for superconductors [PDF]
Within recent developments of density functional theory, its numerical implementation and of the superconducting density functional theory is nowadays possible to predict the superconducting critical temperature, Tc, with sufficient accuracy to ...
Continenza, A. +6 more
core +2 more sources
Effects of Biological Sex and Age on Cerebrospinal Fluid Markers—A Retrospective Observational Study
ABSTRACT Objective Cerebrospinal fluid (CSF) analysis is a key diagnostic tool for neurological diseases. To date, only a few studies have investigated in larger cohorts the effect of age and biological sex on diagnostic markers extracted from CSF. Methods For this retrospective observational study, 4163 CSF findings (2012–2020) were evaluated.
Isabel‐Sophie Hafer +3 more
wiley +1 more source
INTEREST OF ENTRANCE TO HIGHER EDUCATION FOR CLASS XII STUDENTS OF AUTOMOTIVE AND ELECTRONIC SKILLS PROGRAM AT STATE VOCATIONAL HIGH SCHOOL 1 SEYEGAN [PDF]
This study aims to find out the interest of entrance to higher education for Class XII Students of Automotive and Electronic Skills Program at State Vocational High School 1 Seyegan and find out the factors that interest influencing of entrance to higher
Suhirno, Suhirno
core
Validity and Reliability of an Inertial Device for Measuring Dynamic Weight-Bearing Ankle Dorsiflexion [PDF]
A decrease in ankle dorsiflexion causes changes in biomechanics, and different instruments have been used for ankle dorsiflexion testing under static conditions.
Martín Fuentes, Isabel +2 more
core +1 more source

