Results 71 to 80 of about 4,882,480 (354)

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

A Korean version of the Oral Impacts on Daily Performances (OIDP) scale in elderly populations: Validity, reliability and prevalence [PDF]

, 2008
Background: This study aimed to develop a Korean version of the OIDP index for elderly people and to assess the levels of sociodental impacts in an older Korean population.Methods: The OIDP index for elderly people was cross-culturally adapted from ...
Sheiham, A, Sheiham Aubrey, Se-Hwan Jung, Aubrey Sheiham, Jae-In Ryu, Jung, SH, Tsakos, G, Georgios Tsakos, Jung Se-Hwan, Ryu Jae-In, Tsakos Georgios, Ryu, JI   +11 more
core   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Validity of solid-state Li+ diffusion coefficient estimation by electrochemical approaches for lithium-ion batteries [PDF]

, 2022
The solid-state diffusion coefficient of the electrode active material is one of the key parameters in lithium-ion battery modelling. Conventionally, this diffusion coefficient is estimated through the galvanostatic intermittent titration technique (GITT)
Brandell, D., Lacey, Matthew J.,, Brandell, D.,, Thiringer, Torbj\uf6rn, Lacey, Matthew J., Lacey, Matthew,, Chien, Yu Chuan, Thiringer, Torbjorn, Chien, Yu-Chuan, Lacey, Matthew, Chien, Yu Chuan,, Geng, Zeyang, Brandell, Daniel,, Geng, Zeyang,, Brandell, Daniel, Thiringer, Torbjörn,   +15 more
core   +1 more source

Development and Validation of an Instrument for Clinical Evaluation of Nursing Teachers (Student Form) in Ahvaz Jundishapur University of Medical Sciences Iran [PDF]

Strides in Development of Medical Education, 2014
Background & Objective: It is necessary for a correct evaluation to use valid instruments prepared exactly according to the study population and special field This study aimed to determine valid and reliable criteria for clinical evaluation of nursing ...
Fahimeh Sabeti, Hossein Elhampour, Marzieh Shayestehfard, Soheila Sedaghat   +3 more
doaj  

Reliability and validity test of a novel three-dimensional acetabular bone defect classification system aided with additive manufacturing

BMC Musculoskeletal Disorders, 2022
Background Accurate assessment of acetabular defects and designing precise and feasible surgical plans are essential for positive outcomes of hip revision arthroplasty. Additive manufacturing (AM) is a novel technique to print physical object models.
Jingwei Zhang, Yi Hu, Hua Ying, Yuanqing Mao, Zhenan Zhu, Huiwu Li   +5 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Dimensionality and Construct Validity of the Romanian Self-Report Strengths and Difficulties Questionnaire (SDQ) [PDF]

, 2014
The Strengths and Difficulties Questionnaire (SDQ) is one of the most widely utilised measures of behavioural and emotional difficulties among children and young people.
Gavriluta, Christina, Asiminei, Romeo, Gavriluta, Cristina, Sharratt, Kathryn, Jones, Adele, Foca, Liliana   +5 more
core  

Design, validation and dissemination of an undergraduate assessment tool using SimMan® in simulated medical emergencies [PDF]

, 2010
Background: Increasingly, medical students are being taught acute medicine using whole-body simulator manikins. Aim: We aimed to design, validate and make widely available two simple assessment tools to be used with Laerdal SimMan (R) for final year ...
Kirkcaldy, Jo, Macdougall, Colin F., Paskins, Zoe, Peile, Ed, Allen, Maggie E., Fraser, Ian   +5 more
core   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source