Results 201 to 210 of about 5,054,451 (380)
PANCYTOPENIA AND VALPROIC ACID—A POSSIBLE ASSOCIATION [PDF]
, 1995 Dave Robinson +4 more
openalex +1 more source
Tailoring antiseizure treatment with a wearable device: A proof‐of‐concept study in absence epilepsy
Epilepsia, EarlyView.Abstract Objective Typical absence seizures are underreported. We aimed to improve patient care using a wearable electroencephalograph (wEEG) at home and assess a machine learning (ML) pipeline for absence detection. Methods Patients with typical absences used a wEEG device 12–24 h 1 week after antiseizure medication (ASM) adjustments.
Jaiver Macea +4 more
wiley +1 more source
Journal of Pharmacological Sciences, 2005 In patients with hypoalbuminemia, the total serum concentration of valproic acid may offer poor clinical information; however, very few clinical laboratories routinely analyze the free concentration of the drug.
Jesús Hermida, J. Carlos Tutor
doaj
Comparison of Two Binding Equations for Prediction of the Concentration of Unbound Valproic Acid in the Serum of Adult Epileptic Polytherapy Patients [PDF]
, 1996 Yasuo Kodama +6 more
openalex +1 more source
In vitro models of valproic acid to assess neurodevelopmental toxicity: A scoping review
Epilepsia, EarlyView.Abstract Valproic acid (VPA) is a first‐line antiseizure medication (ASM) that is highly efficacious for treating generalized and focal epilepsy disorders. Unfortunately, due to its strong association with teratogenic effects culminating in fetal valproate spectrum disorder (FVSD), which may include neurocognitive and neurobehavioral deficits, the drug
Daniel Sandvik +5 more
wiley +1 more source
Lowering of plasma valproic acid concentrations during concomitant therapy with meropenem and amikacin [PDF]
, 1998 B. J. De Turck +6 more
openalex +1 more source
Epilepsia, EarlyView.Abstract De novo variants in KCNQ2 cause neonatal onset developmental and epileptic encephalopathy (KCNQ2‐DEE; Online Mendelian Inheritance in Man #613720), most often by loss‐of‐function in vitro effects. In this study, we describe a neonatal onset DEE proband carrying a recurrent de novo KCNQ2 variant (c.794C>T; p.A265V) affecting the pore domain of ...
Ingride Luzio Gaspar +6 more
wiley +1 more source
Gomal Journal of Medical Sciences, 2014 Background: Valproic acid is an antiepileptic drug which may cause carnitine deficiency and subsequently hepatotoxicity in the form of necrosis and steatosis.
Syed Khanzada Khan +4 more
doaj
Increase in AP-1 Transcription Factor DNA Binding Activity by Valproic Acid [PDF]
, 1997 Guang Chen +4 more
openalex +1 more source