Results 241 to 250 of about 5,054,451 (380)

The Effect of Carnitine on the Metabolism of Valproic Acid in Epileptic Patients.

, 1992
Kikuo Sakemi, Kiyoshi Hayasaka, Marie Tahara, Yukiaki Sanada, Goro Takada   +4 more
openalex   +2 more sources

Management of T‐cell malignancies: Bench‐to‐bedside targeting of epigenetic biology

CA: A Cancer Journal for Clinicians, EarlyView.
Abstract The peripheral T‐cell lymphomas (PTCL) are the only disease for which four histone deacetylase (HDAC) inhibitors have been approved globally as single agents. Although it is not clear why the PTCL exhibit such a vulnerability to these drugs, understanding the biological basis for this activity is essential.
Ariana Sabzevari, Johnson Ung, Jeffrey W. Craig, Kallesh D. Jayappa, Ipsita Pal, David J. Feith, Thomas P. Loughran Jr, Owen A. O’Connor   +7 more
wiley   +1 more source

Valproic acid induces ferroptosis and suppresses the proliferation of MDA-MB-231 cells by targeting FDFT1. [PDF]

Front Pharmacol
Zhang S, Liu J, Yang Y, Tao R, Ren X, Zhou X, Liu S.   +6 more
europepmc   +1 more source

Clinical studies on serum concentration of free fraction of phenytoin, carbamazepine and valproic acid.

, 1990
Jun Hosoya, HIDEYO NAGAOKA, SYU ISHIKAWA, Yoshito Nakagawa, Yoshiaki Higashitani, Shiro Totsuka   +5 more
openalex   +2 more sources

Influence of Nanoparticles on the Brain-to-serum Distribution and the Metabolism of Valproic Acid in Mice [PDF]

, 2000
J. Darius, Frank Meyer, Bernhard A. Sabel, Ulrike Schröeder   +3 more
openalex   +1 more source

Access to Highly Functional and Polymerizable Carbonate‐Drug Conjugates

ChemSusChem, Volume 18, Issue 11, June 2, 2025.
A generic protocol for drug‐functionalized and carbon dioxide‐based six‐membered cyclic carbonates has been developed. These functional carbonates can be designed for effective ring‐opening polymerization to forge polycarbonates that support a controllable amount of a given drug and additional functionality, opening up complementary strategies for ...
Wangyu Shi, Thirusangumurugan Senthamarai, Matteo Lanzi, Paolo Orlando, Rodrigo Nogués Martín, Arjan W. Kleij   +5 more
wiley   +1 more source

Zinc valproic acid complex promotes osteoblast differentiation and exhibits anti-osteoporotic potential. [PDF]

Open Life Sci
Wang H, Xu Y, Li P, Wu L.
europepmc   +1 more source

Enhancing transporter activity in heterologous expression systems with SAHA: a 2500‐times more potent and odorless alternative to butyrate

FEBS Open Bio, Volume 15, Issue 6, Page 906-913, June 2025.
Heterologous expression of membrane transporters in cultured cells is essential for functional characterization, but is sometimes limited by low activity. Our study compares the HDAC inhibitors butyrate, VPA and SAHA to enhance transport activity. We propose to replace butyrate by SAHA: it is equally effective, devoid of repulsive odor, costs less, and
Svenja Flögel, Maurice Tust, Samira Boussettaoui, Dietmar Fischer, Dirk Gründemann   +4 more
wiley   +1 more source

Analytical evaluation of phenytoin, phenobarbital, valproic acid and vancomycin assays on the Abbott Architect (TM) [PDF]

, 2010
SCHOUWERS, SOFIE, Stove, Veronique, Verstraete, Alain   +2 more
core  

A rare case of factor X deficiency induced by valproic acid. [PDF]

Res Pract Thromb Haemost
Rigon PA, Ernest V.
europepmc   +1 more source