Results 331 to 340 of about 5,054,451 (380)
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Annals of Internal Medicine, 1979
Excerpt To the editor: Valproic acid (Depakene®) is a newly approved drug for the treatment of seizures.
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Excerpt To the editor: Valproic acid (Depakene®) is a newly approved drug for the treatment of seizures.
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2016
A 26-year-old woman (G2P1) is referred to you for consultation. She is in her second month of pregnancy and on valproic acid 1000 mg twice daily for her medically stable Juvenile Myoclonic Epilepsy. She has not had any seizure recurrences in the past year.
Christensen, Jakob +2 more
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A 26-year-old woman (G2P1) is referred to you for consultation. She is in her second month of pregnancy and on valproic acid 1000 mg twice daily for her medically stable Juvenile Myoclonic Epilepsy. She has not had any seizure recurrences in the past year.
Christensen, Jakob +2 more
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JAMA: The Journal of the American Medical Association, 1980
To the Editor.— It is interesting to read inThe Journalthat Livingston et al (241:1892, 1979) found valproic acid to be "of little or no benefit in grand mal, psychomotor, or myoclonic epilepsy of older children." Our experience in a group of 46 mentally retarded patients, ranging in age from 2 to 57 years and receiving valproic acid in dosages of 15 ...
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To the Editor.— It is interesting to read inThe Journalthat Livingston et al (241:1892, 1979) found valproic acid to be "of little or no benefit in grand mal, psychomotor, or myoclonic epilepsy of older children." Our experience in a group of 46 mentally retarded patients, ranging in age from 2 to 57 years and receiving valproic acid in dosages of 15 ...
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Valproic acid and ethosuximide interaction
Annals of Neurology, 1980AbstractThe addition of valproic acid to ethosuximide in treatment to prevent seizures caused increased serum concentration of ethosuximide in four of five patients observed. Ethosuximide levels increased from 73 to 112 m̈g/ml (53% higher), with concomitant toxicity.
Richard H. Mattson +2 more
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The remarkable story of valproic acid
The Lancet Neurology, 2016non ...
Tomson Torbjörn +2 more
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Disposition of valproic acid in man
European Journal of Clinical Pharmacology, 1977The pharmacokinetics of valproic acid (VPA) have been studied in 6 healthy subjects following a single 600 mg dose, and after multiple doses over 12 days (1200 mg daily) of enteric-coated sodium valproate. A time lag before absorption of 1 to 2 h was observed in each subject, and then absorption was rapid, peak concentrations being recorded 3 to 4 h ...
W. Fröscher +4 more
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Comedication of Valproic Acid Is Associated With Increased Metabolism of Clozapine
Journal of Clinical Psychopharmacology, 2018Objectives Valproic acid and clozapine are drugs commonly used in the treatment of schizophrenic and schizoaffective disorders. Pharmacokinetic interactions of valproic acid with several drugs are well known, yet results concerning the interaction with ...
L. Hommers +7 more
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Chronic Valproic Acid Intoxication
Pediatric Emergency Care, 2013Valproic acid intoxication may be associated with cerebral, cardiovascular, respiratory, gastrointestinal, and hematologic complications. We report a case of a 7-year-old girl, epilepsy-treated chronically with valproic acid, sulthiame, and clonazepam, who presented to the emergency room because of a global deterioration during the preceding 2 months ...
Adi Klein-Kremer +3 more
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Archives of Pediatrics & Adolescent Medicine, 1985
Sir.—Dr John B. Isom is to be complimented for his excellent editorial summarizing the problems associated with the use of valproic acid in children.1He makes many excellent points. This editorial serves a very useful purpose for physicians, especially pediatricians, neurologists, and primary care physicians who prescribe anticonvulsant drugs such as ...
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Sir.—Dr John B. Isom is to be complimented for his excellent editorial summarizing the problems associated with the use of valproic acid in children.1He makes many excellent points. This editorial serves a very useful purpose for physicians, especially pediatricians, neurologists, and primary care physicians who prescribe anticonvulsant drugs such as ...
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Valproic Acid and Panic Disorder
The Canadian Journal of Psychiatry, 1990Valproic acid (VA), an anticonvulsant which increases GABAergic transmission was given to patients suffering from recurrent panic attacks. Ten consecutive outpatients were included in this study. After a seven day placebo washout period, patients were given a dose of 500 mg/day, which was gradually increased to a maximum of 2250 mg/day.
Rejean Fontaine +2 more
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