Results 151 to 160 of about 59,251 (307)
Experimental Physiology, EarlyView.Abstract Ageing is a risk factor for cardiovascular and neurodegenerative diseases. The myogenic response in resistance arteries is responsible for basal (myogenic) tone and blood flow autoregulation. G‐protein‐coupled receptors and G12/RhoA/Rho kinase are implicated in myogenic tone (MT), and we aimed to clarify their role in pressure sensing and ...
Gry Freja Skovsted +11 more
wiley +1 more source
Neurohormonal modulation: The new paradigm of pharmacological treatment of heart failure
Revista Portuguesa de Cardiologia, 2019 The current paradigm of medical therapy for heart failure with reduced ejection fraction (HFrEF) is triple neurohormonal blockade with an angiotensin-converting enzyme inhibitor (ACEI), a beta-blocker (BB) and a mineralocorticoid receptor antagonist (MRA)
J. Silva-Cardoso +10 more
doaj +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Overview of multiscale cardiac remodelling in type 2 diabetes and how to model and simulate these changes using a human‐based, multiscale computational framework. Cardiac remodelling in type 2 diabetes occurs at ionic channel, protein, cellular, tissue and whole‐organ level, affecting the electrophysiological function, mechanical
Ambre Bertrand +2 more
wiley +1 more source
Gender specific effects of valsartan on fibrinolysis in hypertensive patients with metabolic syndrome [PDF]
, 2013 Masaaki Miyata +3 more
openalex +1 more source
European Journal of Heart Failure, 2019 To assess differences in diuretic dose requirements in patients treated with sacubitril/valsartan compared with enalapril in the Prospective comparison of ARNI with ACEI to Determine Impact on Global Mortality and morbidity in Heart Failure (PARADIGM‐HF)
O. Vardeny +11 more
semanticscholar +1 more source
Olmesartan‐induced gastritis with no lower gastrointestinal symptoms: A case report
DEN Open, Volume 6, Issue 1, April 2026.Abstract A 74‐year‐old man with decreased appetite, weight, and heartburn was referred to our hospital. His medications included olmesartan. Esophagogastroduodenoscopy (EGD) revealed antral‐dominant erosive gastritis and nodular mucosa. A gastric biopsy revealed inflammatory cell infiltration.
Satoshi Kosaka +2 more
wiley +1 more source
Influence of Mrp2 C24t Genetic Variant on The Pharmacokinetics of Valsartan [PDF]
, 2015 Hyun‐Sub Lee +5 more
openalex +1 more source