Results 171 to 180 of about 247,054 (301)

Toward a relational biodiversity economics: Embedding plural values for sustainability transformation. [PDF]

Proc Natl Acad Sci U S A
Kenter JO, Carmenta R, Christie M, Griffiths H, Ihemezie E, Martin A, Gomez-Osorio MT, Pascual U, Raymond CM, Remoundou K, Waters R.   +10 more
europepmc   +1 more source

PMD5 VALUATION OF NEW DRUG APPLICATIONS OF PHARMACEUTICAL COMPANIES USING COMPOUND OPTION MODELS

, 2002
Danny Cassimon, PJ Engelen, Liesbeth Thomassen, Martine Van Wouwe   +3 more
openalex   +1 more source

The Sequential Compound Option Pricing with Random Interest Rate and Application to Project Valuation [PDF]

, 2006
Meng-Yu Lee, Fang Bo Yeh, An‐Pin Chen
openalex   +1 more source

The influence of ROS1 fusion partners and resistance mechanisms in ROS1‐TKI‐treated non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
This real‐world study of ROS1+ NSCLC highlights fusion diversity, treatment outcomes with crizotinib and lorlatinib, and in vitro experiments with resistance mechanisms. G2032R drives strong resistance to ROS1‐targeted TKIs, especially lorlatinib. Fusion partner location does not affect overall survival to crizotinib or lorlatinib. Findings support the
Fenneke Zwierenga, Christa Dijkhuizen, Patrick Korthuis, Wim Timens, Harry Groen, Jeroen Hiltermann, Anke van den Berg, Lyndsay Drayer, Anthonie van der Wekken   +8 more
wiley   +1 more source

A think-aloud study exploring the application of composite time trade-off and discrete choice experiment methods for valuing the Chinese Short Warwick-Edinburgh Mental Well-being Scale (C-SWEMWBS). [PDF]

Health Qual Life Outcomes
Yiu HHE, Chow LH, Au CCL, Deng EK, Zhao Z, Wei Y, Lee KJ, Huang C, Yang Y, Kang W, Petrou S, Madan J, Chan EW.   +12 more
europepmc   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

The role of the right valuation method in setting the firm's break-even price for mpox (and other) vaccines. [PDF]

BMJ Glob Health
Engelen PJ, Cassimon D.
europepmc   +1 more source

Tumor‐agnostic detection of circulating tumor DNA in patients with advanced pancreatic cancer using targeted DNA methylation sequencing and cell‐free DNA fragmentomics

Molecular Oncology, EarlyView.
We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin, Kjersti Tjensvoll, Karin Hestnes Edland, Satu Oltedal, Herish Garresori, Bjørnar Gilje, Saga Ekedal, Trygve Eftestøl, Jan Terje Kvaløy, Filip Janku, Oddmund Nordgård   +10 more
wiley   +1 more source

Valuation of science and technology innovation enterprises based on XGBoost-GA-BP neural network model. [PDF]

Sci Rep
Shen C, Xiang L, Wang W.
europepmc   +1 more source

Does Recognition Versus Disclosure Really Matter? Evidence from the Market Valuation of Recognition of Employee Stock Option Expenses* [PDF]

, 2007
Flora Niu, Bixia Xu
openalex   +1 more source