Results 171 to 180 of about 248,583 (305)
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Signed Connectedness Among Cryptocurrencies, NFTs, and Foreign Exchange Markets. [PDF]
Entropy (Basel)Yang S, Zhang X, Xu W.
europepmc +1 more source
Value at Risk performance analysis in a period of geopolitical instability: The Ukraine war case
openNell’ambito dei mercati finanziari, il concetto di rischio è sempre stato uno degli argomenti principali. Nel corso degli ultimi anni, l'indicatore "Value at Risk (VaR)" si è affermato come uno strumento fondamentale per valutare le perdite ...
DE VIDI, RICCARDO
core
Modelling and Forecasting Dynamic VaR Thresholds for Risk Management and Regulation [PDF]
The paper presents methods of estimating Value-at-Risk (VaR) thresholds utilising two calibrated models and three conditional volatility or GARCH models.
David E. Allen +2 more
core
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Persistently low blood eosinophils identify a high-risk phenotype in COPD. [PDF]
BMC Pulm MedZhang W +7 more
europepmc +1 more source
Risk Management of Risk under the Basel Accord: Forecasting Value-at-Risk of VIX Futures [PDF]
The Basel II Accord requires that banks and other Authorized Deposit-taking Institutions (ADIs) communicate their daily risk forecasts to the appropriate monetary authorities at the beginning of each trading day, using one or more risk models to measure ...
Michael McAleer +3 more
core
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Mental health and macroeconomics: economic and social determinants that explain suicide in Ecuador. [PDF]
Front Public HealthArgothy A +3 more
europepmc +1 more source
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source