Results 191 to 200 of about 416,632 (304)

A Real-Time Dynamic Warning Method for MODS in Trauma Sepsis Patients Based on a Pre-Trained Transfer Learning Algorithm. [PDF]

Diagnostics (Basel)
Wen J, Liu G, Chang P, Hu P, Liu B, Jiang C, Xu X, Ma J, Zhang G.   +8 more
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Combined pulse wave velocity and triglyceride-glucose index to discriminate large-artery atherosclerosis from small-vessel occlusion in acute ischaemic stroke: a single-centre retrospective study. [PDF]

Front Neurol
Li Z, Hui R, Guo X, Fang Q, Deng H.
europepmc   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Analysis of fossil fuel consumption and socioeconomic drivers of respiratory disease mortality in G7 countries: an ARDL and VAR model approach. [PDF]

Cad Saude Publica
Martins T, Arenhart RS, Reichert B, Jacobi LF, Souza AM.   +4 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

High phenotypic and phytochemical diversity of Bactris gasipaes (Arecaceae) fruits in Ecuador. [PDF]

PLoS One
Romero-Estévez D, Couvreur TLP, Ayala M, Valarezo E, Figueroa JG, Terán MJ, Rivera Á, Montúfar R.   +7 more
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

The impact of China's clean energy market on the market connectivity of rare earth industrial chain. [PDF]

PLoS One
Li J, Zhao Y, Dou S, Zhu Y, Xu D.
europepmc   +1 more source

Risk Measurement-Value at Risk (VaR) Versus Conditional Value at Risk (CVaR): A Teaching Note

Journal of Accounting and Finance, 2018
openaire   +2 more sources