Results 151 to 160 of about 26,602,709 (313)

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Economic Evaluation of Ready-to-Dilute Thiotepa (Tepylute®): Institutional Cost Offsets and Time Savings Compared to Lyophilized Thiotepa in a United States Hospital Pharmacy

open access: yesClinicoEconomics and Outcomes Research
Orlaith Ryan,1 Maurice Clancy,1 Alanna MacDonald,2 Laura Pastor,2 Megan Bourque2 1Shorla Oncology, Clonmel, Co., Tipperary, Ireland; 2Value and Evidence Department, EVERSANA, Burlington, ON, CanadaCorrespondence: Orlaith Ryan, Shorla Oncology, Questum ...
Ryan O   +4 more
doaj  

A Multilinear Singular Value Decomposition

open access: yesSIAM Journal on Matrix Analysis and Applications, 2000
L. De Lathauwer   +2 more
semanticscholar   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Speculation as Surplus-Value

open access: yes, 2019
Speculation is an artist’s capital, enabling the emergence of the new. This is art’s capacity to bring about new frames of reference—new kinds of questions, experiences, events or encounters— to leverage difference in order to open onto an indeterminate ...
Andrea Eckersley (18025996)   +1 more
core  

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

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