Results 121 to 130 of about 1,127,133 (307)
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
European Studies on Land Value Capture of “Unearned Increments”
As a consequence of land use intensification often appear effects that cause remarkable challenges and issues in land management practice. Increase in real property value usually is expected from both public and private investments into improvements of ...
Auziņš, Armands
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Editorial: Insights (January 2020)
Technology Innovation Management Review, 2020 Stoyan Tanev, Gregory Sandstrom
doaj +1 more source
Value Capture in Science:the exchange value paradox
, 2018 Capturing value from scientific knowledge has been described in the context of university-industry collaborations and science-based entrepreneurship. Value capture mechanisms aim to ensure a mainly monetary reward from the exchange of the value created ...
Poetz, Marion Kristin +3 more
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Do Local Elites Capture Natural Disaster Reconstruction Funds? [PDF]
This paper examines the allocation of natural disaster reconstruction funds among cyclone victims in rural Fiji. During post-emergency periods, when good information about cyclone damage is available, do local elites, a powerful minority, capture housing
Yoshito Takasaki
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Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
ESTIMATING REVENUE-CAPTURE POTENTIAL ASSOCIATED WITH PUBLIC AREA RECREATION
A traditional contingent valuation approach and the “"trip response method"” were examined as potential techniques for measuring public area recreation revenue-capture potential.
Bergstrom, John C. +2 more
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