Results 131 to 140 of about 1,127,133 (307)
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Inducing the international diffusion of carbon capture and storage technologies in the power sector [PDF]
Although CO2 capture and storage(CCS) technologies are heatedly debated, many politicians and energy producers consider them to be a possible technical option to mitigate carbon dioxide from large-point sources.
Vallentin, Daniel
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Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Public Value Capture Tools in Turkey
, 2021 Value capture is an umbrella term used to describe a range of financing mechanisms sharing a common rationale that the benefits of public investments and decisions are capitalized into property values and this value increase, namely betterment, plus ...
Yılmaz, Ahmet
core
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Integrated CO2 Capture and Utilization: Toward Value‐Added Products
Interdisciplinary MaterialsCarbon capture, utilization, and storage (CCUS) is widely recognized as an effective strategy for mitigating carbon dioxide (CO2) emissions; however, its large‐scale deployment is constrained by complex multistep processes and high operational costs ...
Guanchu Lu +7 more
doaj +1 more source
Innovation Governance for Value Capture -The Problem and a Proposed Simple Model-based Solution [PDF]
We aim to model the "optimal" choice on internal versus external innovation for value capture of different-sized firms, in the context of multi-level bargaining. We find that size differentials are a major determinant for the choice in hand.
Panagopoulosi, Andreas +1 more
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
, 2013 This thesis has addressed several gaps in the knowledge with regards to the calcium looping cycle for carbon dioxide capture, including identification of engineering challenges associated with the scale-up of the technology to pilot scale and beyond ...
Cotton, Alissa
core
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source